Biomedical Graduate Education

Mastering Your Scientific Cover Letter

By Timothy Ring BGE Career Strategy & Professional Development

A cover letter comprises a crucial component of any application. This post will show you simple steps you can take to ensure your cover letter is professional, clear, and concise. It will also show you how to highlight how well you match with the employer, rather than merely summarizing your CV or resume.

Introduction

Your goal is to grab attention and present an image of who you are professionally in a short paragraph.

  • Identify yourself and your goals – Give a brief introduction of yourself, what position you are applying for, and how you found out about it.
  • Research the employer – Gain a thorough understanding of not just the job description but also the employer’s mission and values, which you should be able to find through a search of their website. If you can’t find anything on their site, this could be a great time to reach out to someone that works there for an informational interview.
  • Introduce the skills you have that make you a match with what the company is looking for – Share what you learned about the employer that you admire. If this is a research assistant position, it may be referencing a publication of the Principal Investigator. If it is a company, you may mention one of their values that really resonates with you, and a very brief reason for why. Overall, focus more on why you would benefit the employer, and not the other way around. This brings us to the last part – close by introducing what skills you bring to the table that make you an ideal candidate for the position. The actual job description is a good place to look to determine which skills you could emphasize! You will expand upon these skills in your cover letter’s body.

The Body Paragraph(s)

Your goal is to show your skills and how they make you a match for the position.

  • Promote the idea that you are a great match with the company – Within a body paragraph, or several paragraphs if you choose, highlight each of the skills you just introduced. We recommend 3 skills so that you show a diverse skill set, but keep the letter brief. One way to format this is shown in our cover letter template . Make sure to emphasize the clear message that you would be a valuable asset to have on the team.
  • Show what value you have brought, and what you will bring – For each skill, demonstrate past experience in which you used and developed that skill, and explain how this will useful for this position and benefit the employer. Try to be as specific as possible both in regards to your accomplishments as well as how your skills align with the employer’s current goals.

The Conclusion

Your goal is to summarize what you shared above and invite follow

  • Summarize – Tie everything together here. Be sure to emphasize how well you match with what the employer is looking for and how your skills will transfer to this new position.
  • Invite follow up – To invite follow up from the employer, close with something such as “Thank you for considering my application. If you have any questions for me, please do not hesitate to contact me by phone or email.” Make sure you have that information provided in your cover letter!
  • Edit – Make sure you proofread and have made your letter as focused and concise as possible. Leave it to sit for a day and then come back to it and trim anything that does not present you as a great match for the company.

This post was adapted in part from a Science Magazine article .

biomedical phd cover letter

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  • How to Write a Cover Letter for PhD Applications

Written by Chris Banyard

An PhD cover letter is one of the documents you may be required to submit as part of a PhD application . It should complement your academic CV and explain why you are applying. PhD cover letters offer you the chance to write with greater flexibility and personality than in other parts of the PhD application. This page will take you through what a PhD cover letter actually is and how to write one, along with some top tips on what to include (and what not to!).

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What is a cover letter for a phd application.

A PhD cover letter is a counterpart to a CV submitted as part of an application for a PhD programme. It is a short essay addressed to a specific individual and written in prose. It should explain your PhD application in your own words, demonstrating what you can offer and why you should be selected.

What is an academic cover letter for?

There are several reasons why the PhD cover letter is important for university admission. It is an opportunity to:

  • Clarify any gaps in the CV and explain certain aspects in further detail. This doesn't mean you should repeat information on your CV (the letter will probably be read in parallel). Rather, it’s a chance to expand on the story that the CV tells and demonstrate your knowledge.
  • Further tailor your PhD application to the project specification. Here, you can address and match your skills and experiences to those asked for by the university or supervisor.
  • Show professional communication skills and enthusiasm . These are important qualities for a postgraduate applicant, but they can be quite hard to show in a CV or application form. Here, you can write in your own words and present your research interests and passion.

Do I need a cover letter for a PhD application?

Many universities require an academic cover letter as part of the PhD application. It is therefore highly likely that you'll have to write at least one. If you're applying for multiple PhD projects then you will need to make sure you tailor your cover letter for each application.

Cover letters vs personal statements for a PhD application

Although there are similarities between a motivation or cover letter and a personal statement , they are different. A cover letter is more functional - it unites and presents your application. A personal statement is more useful for providing detail on your experience, interests and ambitions. If you are submitting both, you may need to keep this in mind and adjust the detail in each.

What if I don’t have research experience?

Although a PhD cover letter is a good place to expand on any research experience and publications you may have, as Bachelors or Masters students you will not be expected to have lots of this.

It’s more important to write with enthusiasm and show your commitment for research. Fortunately, the academic covering letter is an ideal place to show this!

What to include in a cover letter for a PhD application

The first thing you should include in your cover or motivation letter is a few introductory sentences . Outline who you are, what you are currently doing, whether it be a Masters or a job, and what PhD position you’re applying for. Make sure to include the PhD project reference number if one is provided in the description.

Next, you’re going to want to explain why you are applying for the PhD position. It’s a good idea to put your best, most compelling, or most relevant argument first. The earlier that you can make an impact, the more likely the addressee will read further.

Make sure you’re to the point and concise. An academic cover letter may be there to help illustrate your personality and passion but academics do not have the time to read elongated essays.

After detailing why you want to apply for the project, you need to explain why you’re eligible . Present you relevant skills and achievements in a brief and precise manner. Additionally, make sure to back up your claims with evidence.

An important tip is to demonstrate that you have done your research about the PhD project, supervisor and department. Be specific about why you would be a good fit for the this project in particular .

You should also detail clear understanding of the potential research impact the PhD project could have, and your enthusiasm for it. But, make sure your passion is routed in some research. Just discovering the unknown or novel may not be a compelling reason to research your subject.

Overall, the academic cover letter should show a clear identity and personality, while remaining professional. You need to demonstrate why you are a better and more interesting candidate than other applicants for a PhD.

What to avoid in a cover letter for a PhD application

The academic cover letter will accompany the CV , and therefore should not repeat anything on it. You should refer to information but not reiterate it.

You should also avoid listing all of your achievements, experience etc. It is better to focus on the best aspects of your PhD application.

There should be no statements presented without evidence. A PhD supervisor will see through this straight away.

Also, an ideal motivation letter should avoid offering too much information. This includes technical information, jargon and abbreviations. Focus on being clear and concise instead.

Lastly, you should avoid any vagueness, arrogance, or negativity. And make sure there are no typos or grammatical mistakes.

Formatting a cover letter for a PhD application

The formatting rules for an academic covering letter are very similar to those for a CV. Ensure there is correct spelling and grammar throughout, use consistent and clear font, and get the tone right – this should be enthusiastic and assertive without arrogance.

How long should a cover letter be?

The cover/motivation letter for a PhD application should be approximately one A4 page in length, or around 500 words. If necessary, it can be a little longer but should not be longer than two pages.

Organisation

An academic cover letter should have a beginning, middle and end.

The introduction should explain who you are, what you are applying for and how you started this application (i.e. where you heard about the PhD project, or if you have previously met the supervisor). You can also give a brief background about yourself and your research interests.

The main body should cover your skills and achievements as a counterpart to the CV. This should present your convincing argument as to why you should be accepted for a PhD position. You can also present your ideas for your future research.

Finally, the conclusion should explain why you want to study the PhD project and why you are a perfect fit. It should summarise your application as a whole. It can end with a respectful request to take the application further, such as an interview.

Who should a PhD cover letter be addressed to?

A cover letter should be addressed to a named person i.e. “Dear Professor Smith”. For a PhD application, this will usually be the PhD supervisor, but may be a specific person in charge of recruitment.

If you are still unsure who to address the cover letter to, it should be directed to the Head of Department.

Check that you have the correct title for the addressee.

How to end an academic cover letter?

Because the cover letter should be addressed to a named individual, it should be signed off with either “Yours sincerely” or “Kind regards”. Prior to this, it may be worth adding a polite prompt to reply, such as “I look forward to hearing from you”.

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Chris banyard.

Chris helped expand our student advice content in 2018, whilst working towards a PhD at the University of Sheffield. He shared honest and amusing advice on making mistakes, accidental self-sabotaging and managing rejection during a doctorate as well as reflecting on his own experience skipping a Masters before his PhD.

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Biomedical Scientist Cover Letter Guide With Examples

Land your dream job as a Biomedical Scientist with our expert cover letter tips, engaging samples, and key dos & don'ts in our concise guide!

Shaoni Gupta

Shaoni Gupta

Read more posts by this author.

As a Biomedical Scientist, your cover letter is the key to unlocking opportunities and showcasing your potential to the recruiters.

It serves as a bridge between your qualifications and the employer's needs. This makes your cover letter a vital component of your job application.

Therefore, this article will provide essential insights on composing a cover letter highlighting your skills and making you stand out as the perfect example of your experience.

Let us craft a cover letter that sets you on the path to success in your biomedical science career.

Biomedical Scientist Cover Letter Sample (With Experience)

VL_Biomedical Scientist Cover Letter Sample With-Experience

[Jane Doe] [123, Home Street] [Los Angelas , California , 123 456 ] [[email protected]] [ (123)-123-123] [30.2.2023]

[Recipient's Name] [ABC Institution/Company's] [123 Company Street] [Los Angelas , California , 123 456 ]

Dear [Recipient's Name],

I am writing to express my keen interest in the Biomedical Scientist position at [Research Institution/Company's Name] as listed on [job posting source]. With a Master's in Biomedical Science and [X years] of hands-on experience in [ e.g., "molecular biology techniques and genomics"], I am confident in my ability to contribute effectively to your esteemed team.

During my tenure at [Previous Institution/Company], I was actively involved in [specific project or research]. This work honed my laboratory skills and fortified my analytical and problem-solving abilities.

Some of my notable achievements include:

Publication of [X number of] research papers in reputed international journals, focusing on [specific topic, e.g., "gene expression patterns in rare diseases"].

Introduction of an improved [specific technique, e.g., "protein purification protocol"] which enhanced the efficiency by [specific percentage, e.g., "20%"].

Collaboration with cross-functional teams, leading to [specific outcome, e.g., "the development of a potential therapeutic agent for neurodegenerative disorders"].

I am particularly drawn to [Research Institution/Company's Name] due to its groundbreaking work in [give an example of a specific area]. Your commitment to innovative research and development aligns with my professional aspirations and expertise.

Please find enclosed my resume, which describes my academic and professional journey. I would be honored to discuss in detail how my experience and vision align with the goals of [Research Institution/Company's Name]. Thank you for considering my application.

Biomedical Scientist cover letter sample (Without Experience)

VL_Biomedical Scientist cover letter sample Without-Experience

[John Doe] [123, Home Street] [Los Angelas , California , 123 456 ] [[email protected]] [ (123)-123-123] [30.2.2023]

[Recipient's Name] [ABC Institution/Company's ] [123 Company Street] [Los Angelas , California , 123 456 ]

I am writing to express my strong interest in the Biomedical Scientist position at [Hospital or Laboratory Name], as advertised on [Job posting source]. As a recent graduate with a Bachelor's/Master's in Biomedical Science from [Your University Name], I am excited to begin my career in biomedical research and contribute my knowledge, dedication, and passion to your dynamic team.

While I do not possess direct professional experience in a laboratory setting, my academic background has equipped me with a strong foundation in essential laboratory techniques, data analysis, and scientific methodologies.

During my coursework, I had the opportunity to work on numerous research projects, including my thesis on [Briefly describe your thesis topic or any significant projects you've worked on].

My academic journey has also provided me with a comprehensive understanding [format it as per your skills and knowledge]:

  • molecular biology
  • microbiology
  • clinical chemistry

I have developed proficiency in utilizing various laboratory instruments and software, including [Mention any specific equipment or software you are familiar with]. I am confident in my ability to quickly adapt to the tools and technologies specific to [Hospital or Laboratory Name].

I am highly committed to maintaining the highest standards of quality and safety in the laboratory, and I understand the importance of adherence to protocols and procedures.

Thank you for considering my application. I have attached my resume, which details my educational background and relevant coursework. I look forward to hearing from you to discuss the possibility of working with your institution.

How Do You Write a Biomedical Scientist Cover Letter?

1. Research and analyze the job description Ensure that your skills and values align with those of the hospital or laboratory. Then, tailor your cover letter to match their needs.

2. Use relevant keywords You can increase your chances of passing through the applicant tracking systems by using relevant keywords highlighting your hard skills, e.g., "test analysis," "data management," etc.

3. Use statistics to highlight your achievements Provide quantifiable data and statistics to showcase your achievements and skills.

4. Attach your resume Ensure that your resume is attached along with your cover letter.

5. Give references Add references to your cover letter for your work ethic and performance. These references can be from your past employers, academic instructors, etc.

What to include in a biomedical scientist cover letter?

Paint a vivid picture of your passion for biomedical science. Show your recruiters why you would be the perfect fit for their institution. Listed below are key components that will help your cover letter stand out

1. Mention your hard skills and soft skills

Convince the employers that you would be the ideal candidate for the position of biomedical scientist by highlighting your hard and soft skills. A few examples of hard skills and soft skills have been mentioned below

Hard Skills -Laboratory Techniques -Instrumentation -Data Analysis -Sample Handling -Research and Observation

Soft Skills -Attention to details -Analytical thinking -Problem-Solving -Ethical Conduct -Leadership

2. Provide relevant contact details

Ensure the contact details you provided in your cover letter are all correct and up to date.

3. Mistakes to avoid

Lack of clarity: Ensure your cover letter is clear and concise. Avoid overly complex language that might confuse non-specialists who review your application.

Exaggeration and false claims: Making false claims and exaggerating your qualifications and experiences can have serious consequences if discovered.

Generic cover letters: Generic cover letters that don't address the specific job or organization show indifference. Tailor each cover letter to the particular position and company you're applying to.

Ignoring application instructions: Carefully follow any specific application instructions the employer provides. This includes submission format and document naming conventions.

Here's a collection of cover letters for different jobs that you can explore:

Learn how to end a cover letter
Cover Letter for English Teacher
Cover Letter for a position in Chick-fil-A
Cover Letter for Sports Managers
Cover Letter for internship at UN
Cover Letter for Graphic Designers

Key Takeaways

A well-crafted cover letter is essential for showcasing your potential as a Biomedical Scientist.

Your cover letter should demonstrate your enthusiasm and knowledge of the organization. It should showcase a clear alignment between your skills and the job requirements to make a strong impression on prospective employers.

Use relevant keywords in your cover letter to increase your chances of passing through applicant tracking systems.

Ensure your cover letter highlights hard skills (e.g., laboratory techniques and data analysis) and soft skills (e.g., attention to detail, problem-solving, and leadership) relevant to the Biomedical Scientist role.

Verify that your contact details in the cover letter are accurate and up to date.

Craft your cover letter to match the specific job and organization you're applying to. Ensure it aligns with their requirements and values.

Shaoni Gupta

This article has been written by Shaoni Gupta. She works as a content writer at Vantage Lens . Her areas of interest range from art to astronomy. When she's not writing, she is daydreaming about stepping into the worlds of high fantasy novels.

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Cover Letter for PhD Application: Guide for Writing One & Example From a Real PhD Student

  • Klara Cervenanska , 
  • Updated March 27, 2023 9 min read

When applying for a PhD research position, you usually need to submit certain documents, including an academic CV and a cover letter for PhD application .

A PhD cover letter, also referred to as an academic cover letter, should be carefully crafted, well-formatted, and contain specific sections.

We'll show you how to do exactly that, along with a sample of an academic cover letter from a real person admitted to a PhD program at Lyon University in France.

And if you're not sure how to go about writing your PhD CV, check out this article: CV for PhD Application: How to Write One Like a True Scholar (+CV Example) .

Table of Contents

Click on a section to skip

What is an academic cover letter?

What to include in a cover letter for phd application, how to write a cover letter for phd application, how to format an academic cover letter, phd cover letter sample.

An academic cover letter is a document that PhD candidates submit alongside their academic CV when applying for a PhD. 

Essentially, it's a cover letter for a PhD application.

It's not exactly the same as your regular business cover letter. Nor is it the same as a personal statement or a motivation letter .

The purpose of a cover letter for PhD application is to explain to the reader, who's likely a researcher or a professor, what you can contribute to their institution and/or field.

Moreover, in a PhD application cover letter, you should explain why you're a good match for the research position on the program.

Differences between academic cover letter and business cover letter

Both these documents serve different purposes and people use them in different settings:

  • Academic cover letter is used when applying for positions in academia — most often for a PhD. More emphasis should be on education, research background and scholarly accomplishments. Moreover, it should explain what your contribution to the institution or field could be. It should also point the reader to your academic CV.
  • Regular (business) cover letter is normally used when applying for any kind of job . Hence, more emphasis should be on skills and past experience while being tailored to a specific job position. You should also explain why you're a good fit for the position at the given company. It should point the reader to your resume.

There are also other documents people often mistake for an academic cover letter. These include:

  • Motivation letter is especially relevant for fresh graduates when applying to a university, a non-profit organization, or voluntary work. A motivation letter focuses more on your interests and motives for applying.
  • Personal statement. Also used in an academic setting. It's always written by an applicant, often a prospective student, applying to college, university, or graduate school. You explain why you've chosen a particular course and why you'd be good at it. Other names include a statement of purpose or a letter of intent .

Like every cover letter, an academic one also needs to include specific elements and content sections. These are:

  • Header. Here, provide your contact information, such as your name, address, phone number, and email in the header of the document.
  • Formal salutation. In an official letter like this one, you should address the reader in a professional and formal way. If you know who'll be reading your cover letter, go with Dear Dr. [Surname] or Dear Professor [Surname] . If you don't, go with Dear Sir/Madam .
  • The specific PhD program or position. Clearly state in your letter which research position you're applying for or the name of the PhD program. A cover letter is usually read before a CV, so you need to make sure everything is clear.
  • Your motivation. Explain why you're interested in the specific PhD position — it's one of the key elements you should include.
  • Your academic background. Now, we don't mean you should list in detail every single university course you ever took. Instead, focus on the most relevant course for the PhD and describe in detail what you learned, any projects you worked on, why it was interesting (and optionally, what knowledge gap you identified). In this way, you also show a certain level of understanding of the field.
  • Your ambition. Briefly mention what your ambitions, intentions, and plans are regarding your contribution to the field when securing your PhD position. How is your research going to enrich the field? How will the institution benefit from it?
  • Conclusion. Keep the conclusion short. Contrary to a regular cover letter ending , there's no place for reiterating everything here. Simply thank the reader for your consideration and prompt them to read your academic CV.
  • Formal sign-off. Just pick from the usual: Sincerely, Respectfully, Regards... Then throw in your full name in the following line.

And that's all you need to include!

Now, let's take a look at how to write your cover letter step-by-step.

Applying for a PhD will be a lot less stressful if you follow these tips on how to write a cover letter for a research position:

Consider researching the background of the organization, department, ongoing research projects, and their past and current projects. All that before you start writing your cover letter. Knowing these things will help you tailor your letter to the specific PhD opening.

Before you actually start writing, try to sit down and take a moment to think first. Assess how your past experiences helped you prepare for the PhD position and scribble down those that are most relevant and significant for the specific program. These include any research experiences, research projects, courses, or internships.

In the first few sentences of your letter, you need to convey some basic information about yourself and what specific position you're applying for. The opening should also state firmly why you're a strong candidate for the position/program, by using a persuasive and convincing wording. Here's an example: "As an MChem Chemistry graduate with a narrow focus on the sustainable synthesis of biologically active molecules from the University of Dundee, I am excited to apply to a "Synthesis Of Small Molecule Inhibitors Using Enzymes" PhD programme at an institution with such a strong foundation and numerous research groups in this field."

This is the place where you may explore more extensively on the educational journey that brought you here. Set the foundation for demonstrating how your Master's degree and research experience seamlessly translate into the next phase — the PhD program. Emphasize how your thesis contributes to the field's body of knowledge. Mention any other publications that support your thesis. And, if you can, identify any knowledge gaps or topics that can be explored further.

This paragraph provides the opportunity to neatly tie in together everything the reader has learned about you so far. You can show how your previous experience, coupled with what you'll learn during the PhD program, will come together to produce something novel to enrich the field. First, identify the courses or topics within the PhD program that interest you the most and how they relate to you developing your research further. Second, introduce your future research aspirations and goals. Third, point out how this future work will enrich the field and what will the intellectual merit be.

When ending your PhD cover letter, briefly refer your reader to your academic CV and encourage them to examine all of the remaining projects, courses, publications, or references . Finally, thank the reader for their time and consideration and let them know you look forward to hearing from them. Sign off.

Put the letter in a drawer and don't think about it for a day or two. Then, when you read it again, you'll have a fresh pair of eyes to see the cover letter in a new light. Maybe you decide some things are redundant, or you think of something that's more relevant. Or you know, find a typo here and there.

Just like an academic cover letter needs to contain certain content components, the formatting should also align with the structural expectations for this type of document.

How long should a cover letter be? How to finish a cover letter? And what about the cover letter font and spacing?

Here's a recommended academic cover letter format:

  • Length. While STEM PhD candidates should aim for half a page to one page, humanities candidates can do 1–2 pages.
  • Font. Use one of the classics: Times New Roman, Calibri, or Arial. Just no Comic Sans, we beg you. Keep the size between 10–12 points. Also remember to keep the text clean — no underlining, no bolding, and no color. However, you can use italics if appropriate.
  • Spacing. Cover letter spacing isn't complicated. Just single-space your text, make sure there's a space between each paragraph, and leave a space between the concluding paragraph and your formal sign-off.
  • Margins. The only rule here is that the margins on your cover letter should match those on your CV.
  • Consistence with your CV. Your academic cover letter should match your academic CV in all formatting aspects — including the cover letter font and spacing. For example, Kickresume lets you choose a matching template for your CV and your cover letter, so no need to worry about this.

If the institution provided any instructions for formatting your academic cover letter, don’t get creative and follow their guidelines.

Finally, to help you tie everything we talked about together, here's a cover letter sample from a real person admitted to a PhD program at Lyon University in France.

These things ensured Herrera's cover letter was successful:

  • She clearly states her motivation in the opening. In the first two paragraphs, Herrera introduces herself and her motivation to apply for the given PhD program.
  • She describes educational and research background thoroughly. The main body of the letter is dedicated to describing Herrera's educational background, research projects, internships, and skills acquired throughout the way.
  • She presents research aspirations in the letter. Herrera writes: "I have a history of proven results and profound findings. Given opportunity, I’m confident in my abilities to earn similar ground-breaking results while being part of your team."

Even though this example lacks some of the key elements, such as mentioning the specific PhD program or identifying the topics within the PhD program that interest her the most, this PhD cover letter still managed to impress the University of Lyon.

Lyon University PhD Student Cover Letter Sample

Klara graduated from the University of St Andrews in Scotland. After having written resumes for many of her fellow students, she began writing full-time for Kickresume. Klara is our go-to person for all things related to student or 'no experience resumes'. At the same time, she has written some of the most popular resume advice articles on this blog. Her pieces were featured in multiple CNBC articles. When she's not writing, you'll probably find her chasing dogs or people-watching while sipping on a cup of coffee.

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  • Biomedical Science cover letter examples

Andrew Fennell photo

To secure Biomedical Science jobs, firstly you need to get your CV in front of the employer.

And to do that you will need a strong cover letter.

But writing a cover letter which stands out from the crowd and encourages recruiters to read your CV is not always easy.

So, we have created 3 Biomedical Science cover letter examples to give you some inspiration, along with a full guide on how to create your own winning cover letter.

Guide contents

How to write a Biomedical Science cover letter

  • What to include in a Biomedical Science cover letter

CV templates 

Biomedical Science cover letter example 1

Biomedical Science cover letter 1

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Biomedical Science cover letter example 2

Biomedical Science cover letter 2

Biomedical Science cover letter example 3

Biomedical Science cover letter 3

These 3 Biomedical Science cover letter examples will provide you with some good ideas on how to format a cover letter, along with the type of message you should be trying to put across to recruiters .

To further understand exactly how you can write a cover letter that will get you noticed, check out our further guidance.

Here’s how you can write your own eye-catching cover letter, broken down into simple steps.

How to write a cover letter

Write your cover letter in the body of an email/message

Type the content of your cover letter directly into the email you are sending, or if you are applying via a job board, directly into their messaging system.

The reason for doing this it to ensure that your cover letter gets seen instantly and you can start connecting with the recruiter as soon as they open your message.

If you attach your cover letter as a separate document, the recipient will have to open up the document, which will slow the process down, or make them less likely to even open your cover letter – which could mean your application gets skipped over.

Cover letter writing

Start with a friendly greeting

Cover letter address

To kick your cover letter off, start with a friendly greeting to build rapport with the recruiter instantly.

Your greeting should be personable but professional. Not too casual, but not too formal either

Go with something like…

  • Hi [insert recruiter name]
  • Hi [insert department/team name]

Avoid old-fashioned greetings like “Dear sir/madam ” unless applying to very formal companies.

How to find the contact’s name?

Addressing the recruitment contact by name is an excellent way to start building a strong relationship. If it is not listed in the job advert, try these methods to find it.

  • Check out the company website and look at their  About page. If you see a hiring manager, HR person or internal recruiter, use their name. You could also try to figure out who would be your manager in the role and use their name.
  • Head to LinkedIn , search for the company and scan through the list of employees. Most professionals are on LinkedIn these days, so this is a good bet.

Identify the role you are applying for

After you have greeted the recruiter, it’s important to state the job you are applying to.

Recruiters are often managing multiple vacancies, so they need to know exactly which job you are referring to.

Be as specific as possible and use a reference number if you can find one.

Here are some examples you can use;

  • I am interested in applying for the role of admin assistant with your organisation.
  • I would like to apply for the role of Sales assistant (Ref: 4057393)
  • I would like to express my interest in the customer service vacancy within your retail department
  • I saw your advertisement for a trainee project manager on Reed and would like to apply for the role.

See also: CV examples – how to write a CV – CV profiles

Highlight your suitability

The main purpose of your cover letter is to excite recruiters and make them eager to open your CV. And you achieve this by quickly demonstrating your suitability to the job you are applying for.

Take a look at the job adverts you are applying for, and make note of the most important skills being asked for.

Then, when you write your cover letter, make your suitability the focal point.

Explain how you meet the candidate requirements fully, and why you are so well suited to carry out the job.

This will give recruiters all the encouragement they need to open your CV and consider your application.

Cover letter tips

Keep it short and sharp

It is best to keep your cover letter brief if you want to ensure you hold the attention of busy recruiters and hiring managers. A lengthy cover letter will probably not get read in full, so keep yours to around 3-6 sentences and save the real detail for your CV.

Remember the purpose of your cover letter is to quickly get recruiters to notice you and encourage them to open your CV, so it only needs to include the highlights of your experience.

Sign off professionally

To round of your CV, you should sign off with a professional signature.

This will give your cover letter a slick appearance and also give the recruiter all of the necessary contact information they need to get in touch with you.

The information to add should include:

  • A friendly sign off – e.g. “Kindest regards”
  • Your full name
  • Phone number (one you can answer quickly)
  • Email address
  • Profession title
  • Professional social network –  e.g. LinkedIn

Here is an example signature;

Warm regards,

Jill North IT Project Manager 078837437373 [email protected] LinkedIn

Quick tip: To save yourself from having to write your signature every time you send a job application, you can save it within your email drafts, or on a separate documents that you could copy in.

Cover letter sign off

What to include in your Biomedical Science cover letter

So, what type of information should you write about in your Biomedical Science cover letter?

The specifics will obviously depend on your profession and the jobs you are applying to, but these are the key areas you should be covering.

  • Your industry experience – Tell recruiters the types of companies you have been working for and the roles you have held in the past.
  • Your qualifications – Highlight your most important relevant qualifications to show employers you are qualified to do the roles you are applying for.
  • The impact you have made – Demonstrate the positive impact you have made for employers in previous jobs. Have you saved money? Improved processes? Made customers happy?
  • Your reasons for moving – Employers will want to know why you are leaving your current/previous role, so provide them with a brief explanation here.
  • Your availability – When will you be able to start a new job ? Check your current contract to find out your notice period if you are in a position already.

To round up

Writing an impressive cover letter is a crucial step in landing a Biomedical Science job, so taking the time to perfect it is well worth while.

By following the tips and examples above you will be able to create an eye-catching cover letter that will wow recruiters and ensure your CV gets read – leading to more job interviews for you.

Good luck with your job search!

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How to Write a PhD Cover Letter With Examples

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biomedical phd cover letter

A well-crafted cover letter is an essential component of your PhD application package. It provides an opportunity to introduce yourself, highlight your qualifications, and express your enthusiasm for the program. While your academic CV provides a comprehensive overview of your academic and professional background, the cover letter allows you to personalise your application and make a strong impression on the admissions committee. This article will explore what a cover letter for PhD application is and will guide you through the process of writing a compelling cover letter for your PhD application, including tips and examples.

What is a PhD Cover Letter?

A PhD cover letter is a crucial document that accompanies your application for a doctoral programme. It serves as a personal introduction to the admissions committee, outlining your research interests, academic background, and why you are a strong fit for the programme. Unlike a CV, which lists your qualifications, the cover letter highlights your motivation, research goals, and how your past experiences align with the programme’s strengths. It’s your opportunity to make a compelling case for why you should be selected, showcasing your passion for the subject and your readiness for the challenges of a PhD.

Understanding the Purpose of a PhD Cover Letter

A cover letter for a PhD application serves several purposes:

Introduction: The cover letter introduces you to the admissions committee, providing a brief overview of who you are and why you are applying to the program.

Personalisation: It allows you to personalise your application by highlighting specific aspects of your background and qualifications that are relevant to the program.

Demonstration of Interest: The cover letter demonstrates your enthusiasm and interest in the program, showcasing your motivation for pursuing a PhD and your alignment with the program’s goals and values.

Additional Information: It provides an opportunity to address any gaps or inconsistencies in your academic CV and provide additional context or explanations where necessary.

How to Write a PhD Cover Letter

1. Address the Letter Appropriately

Begin your cover letter with a professional greeting, addressing the recipient by name if possible. If you are unsure of the recipient’s name, use a generic greeting such as “Dear Admissions Committee.”

2. Introduce Yourself

Start by introducing yourself and stating the purpose of your letter. Mention the specific PhD program you are applying to and briefly explain why you are interested in the program.

3. Highlight Your Qualifications

Highlight your academic and professional qualifications, focusing on experiences and achievements that are relevant to the program. Emphasise any research experience, publications, presentations, or awards that demonstrate your readiness for doctoral study.

4. Connect Your Background to the Program

Demonstrate your familiarity with the program by discussing how your background and interests align with the program’s focus areas, faculty expertise, and research opportunities. Explain why you believe the program is a good fit for your academic and career goals.

5. Express Enthusiasm

Express genuine enthusiasm and excitement for the opportunity to join the program. Convey your passion for your field of study and your eagerness to contribute to the academic community.

6. Be Concise and Clear

Keep your cover letter concise and to the point, focusing on the most relevant information. Avoid unnecessary details or lengthy explanations.

8. Proofread Carefully

Proofread your cover letter carefully to ensure it is free of typos, grammatical errors, and formatting issues. Consider asking a trusted friend, mentor, or colleague to review your letter for feedback.

How to Format a PhD Cover Letter?

When applying for a PhD programme, a well-formatted cover letter is essential for making a strong impression. The typical PhD cover letter format follows a clear and professional structure. Start with your contact information at the top, followed by the date and the recipient’s details. Begin with a formal salutation, such as “Dear Dr. Smith” or “Dear Admissions Committee.”

In the introduction, briefly state your purpose and mention the specific PhD programme you’re applying for. The body should include 2-3 paragraphs: one detailing your research interests and how they align with the programme, another highlighting your relevant academic background and experiences, and a final paragraph explaining why you’re particularly interested in this programme and institution.

Conclude with a strong closing statement, expressing your enthusiasm for the opportunity and your readiness to discuss your application further. Finally, end with a professional sign-off, such as “Sincerely,” followed by your name.

Example of a PhD Cover Letter

Here’s an example of how to structure a cover letter for a PhD application:

I am writing to express my enthusiastic interest in the [PhD Program Name] at [University Name], as advertised in [Source of Advertisement]. With a strong background in [Your Field of Study] and a passion for [Specific Research Interest], I am confident that I would make a valuable addition to your academic community.

I recently completed my [Degree Level] in [Your Field of Study] at [Your University], where I graduated with honours. My academic coursework and research experiences have equipped me with a solid foundation in [Relevant Skills or Knowledge], preparing me for advanced doctoral study. I am particularly drawn to [Specific Aspect of Program], and I am excited about the opportunity to collaborate with esteemed faculty members such as [Professor’s Name].

In addition to my academic achievements, I have [Briefly Mention Relevant Experience or Accomplishments], which I believe demonstrate my readiness for doctoral study. I am eager to further explore [Specific Research Interest] and contribute to the ongoing research efforts at [University Name].

I am impressed by the innovative research being conducted at [University Name] and the interdisciplinary approach to [Your Field of Study]. I am particularly interested in [Specific Research Project or Area], and I am eager to explore potential collaborations with faculty members and fellow students.

Thank you for considering my application. I am excited about the possibility of joining the [PhD Program Name] at [University Name], and I look forward to the opportunity to contribute to the academic community. I am available for an interview at your earliest convenience.

[Your Name]

The Bottom Line

A well-written cover letter can significantly enhance your PhD application and set you apart from other candidates. By following these tips and using the example provided, you can craft a compelling cover letter that highlights your qualifications, demonstrates your enthusiasm for the program, and convinces the admissions committee of your suitability for doctoral study. Remember to tailor your cover letter to each program and provide specific examples that showcase your strengths and alignment with the program’s goals. With careful preparation and attention to detail, you can increase your chances of success in the competitive world of PhD admissions.

Maximise Your PhD Application

Let us guide you through your  PhD application process with our comprehensive application support package . Tailored to your specific needs and subject area, our nine-element package is designed to assist students applying to PhD programmes in English-language universities across the UK, US, Australia, and more. 

It includes a consultation session, university recommendations, personalised letters of introduction, funding advice, CV enhancement, personal statement drafting, PhD title exploration, a full proposal, and miscellaneous application support. Get in touch to learn more about how we can support your PhD application.

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Biomedical Scientist Cover Letter Examples & Writing Tips

Use these Biomedical Scientist cover letter examples and writing tips to help you write a powerful cover letter that will separate you from the competition.

biomedical phd cover letter

Table Of Contents

  • Biomedical Scientist Example 1
  • Biomedical Scientist Example 2
  • Biomedical Scientist Example 3
  • Cover Letter Writing Tips

Biomedical scientists conduct research to improve the understanding of human health and disease. They may also develop new treatments for diseases.

To land a job as a biomedical scientist, you’ll need to write a cover letter that showcases your skills and experience. Check out the examples and tips below to learn how to write a cover letter that stands out.

Biomedical Scientist Cover Letter Example 1

I am excited to be applying for the Biomedical Scientist position at ABC Labs. I have a Ph.D. in Molecular Biology and more than five years of experience in the field of biomedical research. I am confident that I have the skills and experience to excel in this role and contribute to ABC Labs’ cutting-edge research initiatives.

I have a proven track record of success in biomedical research. In my previous role at DEF Research, I was responsible for designing and conducting experiments, analyzing data, and preparing reports. I also played a key role in developing a new research methodology that is now being used by the team at DEF Research.

I am passionate about biomedical research and I am excited to share my knowledge and skills with the team at ABC Labs. I am confident that I can make a significant contribution to your team and help you achieve your research goals.

Thank you for your time and consideration. I look forward to hearing from you soon.

Biomedical Scientist Cover Letter Example 2

I am writing to apply for the Biomedical Scientist position that was recently advertised on your company website. I am confident that I have the skills and qualifications that you are looking for, and I am eager to put my experience to work for your team.

I have been working as a Biomedical Scientist for the past three years and have developed a strong understanding of the field. I am knowledgeable in all aspects of the job, from conducting research to analyzing data to preparing reports. I am also an effective communicator and have excellent problem-solving skills.

Most importantly, I am passionate about biomedical science and am always looking for new ways to improve my skills and knowledge. I am confident that I can be a valuable asset to your team and am eager to contribute to your organization.

Biomedical Scientist Cover Letter Example 3

I am writing to express my interest in the biomedical scientist position that you have posted. I believe that my background and experience make me an excellent candidate for this position.

I have a Master of Science degree in Biomedical Sciences from the University of Michigan, Ann Arbor. My undergraduate degree is in Biology with a minor in Chemistry from the University of Wisconsin, Madison. I also hold a certificate in Molecular Biology from the University of Wisconsin, Madison. I have been working as a research assistant at the University of Wisconsin, Madison since May 2010.

My research interests include molecular biology, biochemistry and cell biology. I have extensive experience in molecular cloning, DNA sequencing, protein expression and purification, immunoblotting and ELISA assays. I am proficient in using various laboratory instruments such as centrifuges, incubators, microscopes and spectrophotometers. I am also skilled in using various computer programs such as Microsoft Office Suite, Excel, PowerPoint, Word and Access.

I am confident that my skills and experience will be an asset to your organization. I would welcome the opportunity to meet with you to discuss how my qualifications can best be utilized by your company.

Biomedical Scientist Cover Letter Writing Tips

1. highlight your experience.

When writing a cover letter for a biomedical scientist position, it’s important to highlight your experience and how it will help you in this new role. Some great ways to do this include:

  • Mentioning specific projects you’ve worked on in the past and how you helped contribute to the team’s success.
  • Detailing the type of research you’re most interested in and how your skills and experience will help you in this area.
  • Listing any awards or recognition you’ve received for your work in the biomedical sciences field.

2. Customize your cover letter

Just as you would for any other job application, customize your cover letter by highlighting how your skills and experience make you the perfect candidate for the position. For example, if the job listing mentions that the company is looking for someone with experience in a particular area of research, be sure to mention any relevant projects you’ve worked on in the past.

3. Show your passion for the field

One of the best ways to show employers that you’re passionate about the biomedical sciences field is by using specific examples from your past work experiences. For example, you could talk about how you became interested in the field, the type of research you’re most interested in, or any challenges you’ve faced while working in the biomedical sciences field.

4. Proofread your cover letter

Just as you would for any other job application, proofread your cover letter for mistakes in spelling, grammar, and sentence structure. This is an important step in ensuring that your application is free of errors and looks professional.

Childcare Worker Cover Letter Examples & Writing Tips

Production technician cover letter examples & writing tips, you may also be interested in..., greenhouse grower cover letter examples, ob nurse cover letter examples & writing tips, accounting director cover letter examples & writing tips, benefits coordinator cover letter examples & writing tips.

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  • Published: 14 October 2022

How to make cover letters instructive

Nature Biomedical Engineering volume  6 ,  pages 1087–1088 ( 2022 ) Cite this article

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Succinctly convey the study’s context, emphases, implications and limitations.

The title of this Editorial may be read as implying that cover letters to articles submitted to Nature Biomedical Engineering are neither useful nor informative. Indeed, most aren’t. We find that many cover letters for research articles express excitement about the work, restate the abstract of the manuscript, declare that the findings constitute a major advance and emphasize the importance of the main research topic. They also typically list authors, suitable reviewers and excluded experts, and any competing interests and other confidential information; yet most of this information is requested by the manuscript submission system or can be provided through it.

biomedical phd cover letter

Excitement, prominent advances and topical importance are, perhaps expectedly, more commonly relayed by authors than perceived or judged by editors (especially by those with a mindset for selectivity). Naturally, one’s own work is a labour of effort and passion; yet it is difficult to transmit enthusiasm to an editor accustomed to reading, often cursorily, many similarly worded cover letters each week. Novel, promising and transformative work, and platform technology with untapped potential are examples of swiftly skipped words in the angular gyrus of an editor’s brain as they skim through a cover letter to rapidly find the most useful bits of information.

There’s more than love for one’s work shaping the style of cover letters. Competition for publishing in a journal that peers perceive to be of high reputation drives many authors to overemphasize the findings of their work and the broader relevance of the subject area 1 . And misgivings about the work being misjudged by an editor insufficiently knowledgeable about the topic may drive some authors to avoid conveying seemingly complex context or background information, and to magnify the implications of their results.

It is therefore unsurprising that some editors disregard cover letters when assessing the suitability of a manuscript for their journal, or read the manuscript before opening the cover-letter file so as to appreciate and assess the work in the form meant to be communicated. Also, the widely held belief that editors of Nature-branded journals select manuscripts largely on the basis of the cover letter is a myth; manuscripts are examined 2 . Are cover letters for first submissions therefore a wasted effort? Are they an unhelpful relic of the pre-internet era? Do they bias manuscript selection? Many arguments can be made for and against these questions. Instead, discussing how cover letters accompanying first submissions of original research articles can be made more instructive would be more fruitful. That’s our aim for the remainder of this piece.

First, and foremost, know your audience. Manuscripts are written for the many; cover letters should be written for an audience of one (or for a team of very few). When writing a manuscript, knowing your intended audience primordially means appropriately crafting the context of the scientific story 3 . Similarly, consideration of the current scientific experience of the manuscript’s prospective handling editor and of their editorial colleagues — should this information be known or available — can inform how the cover letter is framed. Has the journal published related work? Does it have a reputation for quality in the subject area or for publishing similar types of scientific advances? Are the editors likely to be familiar with current challenges and opportunities in the field, and knowledgeable about its standards of rigour and reporting? Are the editors aware of any relevant controversies?

Second, help the editors understand and assess the main contributions of your work. At Nature Biomedical Engineering , for research manuscripts that fit the journal’s scope we assess the degree of advance, broad implications and breadth and depth of the work. To perform this task well, we need to place the manuscript in its appropriate context 4 . We find that a cover letter is particularly informative when it helps us to identify the relevant type of advances in the study. Do the authors feel that the main contribution of the work involves the development of new technology to widen its biomedical applicability? Or does the value of the work mostly lie on the performance and translatability of a slightly improved workflow? Are any of the methods or their implementation new? Was the study’s aim to minimize the usability and cost of a device, or to expand its functionality? Is the mechanism of action underlying the discovered phenomena a notable contribution? And are the mechanistic insights being leveraged to improve the understanding of the disease or the intervention? We also appreciate it when cover letters provide suitable context for the work: for instance, which recently published studies are most relevant, and why? Is the work merely using state-of-the-art technology or methodology, or building on it? Has the same problem been addressed by other approaches? Has the same hypothesis been investigated from different angles? What types of validation support the robustness of the findings?

Third, describe the realistic implications of the work. The temptation is to dream big; yet, the credibility of the inferences improve when they are suitably constrained. Hence, state the main challenges that lie in the way. Similarly, describe the study’s limitations and whether they arise from the assumptions made, or from the methods, models or data acquired or used.

The style and format of research manuscripts are constrained for good reasons: they make it easier to find and interpret the information. The freedom of free-form writing can make cover letters more challenging to write well. We can offer a few more pieces of advice: constrain their length, structure and detail 5 , and explain your work and its context accessibly 6 . And, as if writing for a semi-supervised learning agent (pictured), use natural language.

Nat. Biomed. Eng. 1 , 771 (2017).

Nature 556 , 5 (2018).

Nat. Biomed. Eng. 2 , 53 (2018).

Nat. Biomed. Eng. 6 , 677–678 (2022).

Nat. Biomed. Eng. 5 , 1111–1112 (2021).

Nat. Biomed. Eng. 6 , 105 (2022).

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The Cover Letter

A cover letter can be used for many different things (job applications etc). on this course the cover letter is intended for manuscript submissions . it is important to be polite, use the name of the person you are writing to if possible. summarize the main findings of your work, and describe why this would be interesting for the readers of the journal. here it of course helps if you have a major finding. one school of cover letter writing insists you make it loooong, about two-three pages. the theory is that you thereby force the editor to commit his/her time to it, and that this makes a subconscious impact of that it is somehow important. by contrast, a very short letter is more easily forgotten and dismissed. but you need also to check the instructions for authors, there may be limits or guidelines you should adhere to. i am more sort of in favor of the short cover letter, focused on the main, strong findings, so that you don't bore the editor to death with fluff.  here is a brief template: 'dear sirs/madams, enclosed please find a manuscript entitled 'xxxxxxxxx', where we show for the first time that blablabla. these findings should be of interest for readers of the journal, especially for those in the field of yyyyyyyyy. others have previously shown that blablabla, however, here we blablabla and blablabla. this is in contrast with the current research of blablabla and blablabla. looking forward to hearing from you. sincerely, ...' when re-submitting a revised manuscript , you also add a cover letter, but now typically appending an itemized rebuttal list, addressing the concerns of the reviewers, point-by-point. you can find some examples of such on the previous page.  .

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Scientific Publishing in Biomedicine: How to Write a Cover Letter?

Zahra bahadoran.

1 Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Parvin Mirmiran

Khosrow kashfi.

2 Department of Molecular, Cellular and Biomedical Sciences, Sophie Davis School of Biomedical Education, School of Medicine, City University of New York, New York, USA

Asghar Ghasemi

3 Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

A cover (covering) letter is a brief business letter introducing the scientific work alongside the submission process of a manuscript and is required by most scientific peer-review journals. A typical cover letter includes the name of the editor and the journal, date of submission, the characteristics of the manuscript, the importance of the work and its relevance to prospective audiences, declarations such as author agreements, conflicts of interest statement, funding source (s), and ethical statements. The letter also includes the contact information of the corresponding author (s) and may also include suggestions of potential reviewers. Spending enough time to draft an informative, comprehensive, and concise cover letter is quite worthwhile; a poorly drafted one would not persuade the editor that the submitted work is fit for publication and may lead to immediate rejection. Here, we provide a practical guide to draft a well-written, concise, and professional cover letter for a scientific medical paper.

The Cambridge dictionary defines a cover letter as “a letter that contains information about the thing it is sent with”. The cover letter is commonly known as a motivation letter submitted along with the curriculum vitae (CV) or a job application for employment ( 1 ) or academic position ( 2 ), and it is not clear why and how it was introduced into the scientific field ( 3 ). In scientific writing and publishing, a cover/covering letter is a letter to the editor’s target journal ( 4 ).

Providing a cover letter alongside the submission process is now required by most scientific journals. In fact, some high-quality and prestigious journals pay specific attention to the cover letter ( 3 ). Amongst the different steps of the publication process, the cover letter is the last step and is often overlooked ( 5 ). One of the most common complaints voiced by editors regarding submitted manuscripts is that the authors neglect to write a well-written cover letter, including a statement justifying the importance of their work ( 6 ). Missing this opportunity may have unintentional consequences, rejection without further consideration instead of being sent for external peer-review ( 5 , 6 ). Contrary to this view, some believe that the cover letter’s content overlaps with the manuscript’s abstract and gives mostly redundant information already found within the online submission system ( 3 ). The cover letter may also be a “misleading commercial advertisement” where it would not represent the content of the manuscript ( 3 ).

Although many editors may not read or seriously consider the cover letters of the submitted manuscripts ( 3 , 4 ), neglecting the importance of the cover letter may be a risk for the authors. Therefore, spending an adequate amount of time to write a coherent and persuasive cover letter is worth it. Following our previous publication on choosing a journal in a new series entitled Scientific Publishing in Biomedicine ( 7 ), here, we provided a practical guide to draft a well-written, professional, and concise cover letter needed to be accompanied by an original scientific paper, either with the initial submission or subsequently at revision/resubmitting stage. Since there are subtle differences in writing a cover letter for an original research paper versus a review article or an opinion, some points for drafting a cover letter for such papers are also discussed.

2. The Function of the Cover Letter

A cover letter is “a brief business letter”, which introduces the submitted manuscript to a prospective editor (s) ( 8 ). There are essentially two types of letters; the first is the one that is initially submitted with the manuscript (cover letter), and the second is when a revision is being submitted (revised letter). The first letter introduces the work at the initial manuscript submission ( 9 ), while the second one is needed following an invitation to revise and resubmit the manuscript. Here, the authors respond to the suggestions/criticisms of the reviewers ( 10 ). In this paper, “cover letter” and “second letter” refer to the first/submit letter and the revised letter, respectively.

A well-written cover letter is an effective tool for authors to sell their work to the journal editor and make a “good first impression”. A cover letter is a summary that highlights the main points, emphasizes the novelty, and communicates the potential implications of the submitted work ( 3 ). A cover letter allows the authors to persuade the editors regarding the novelty/originality and significance of the research in a less formal manner than in the manuscript itself ( 6 ). A well-written and informative cover letter helps the journal’s editor to be informed about the work and its significance. Regardless of the novelty and significance of the submitted manuscript, editors may miss those points without providing insights in a cover letter ( 5 ).

3. The Content of a Cover Letter

3.1. first cover letter (submit letter).

One point of view is that the cover letter’s content should be covered in the manuscript’s abstract ( 3 ). A typical cover letter includes the name of editor (s) and the journal, date of submission, the characteristics of the manuscript (i.e., title, type of the manuscript, e.g., review, original, case report), the importance of the work and its relevance to the readership of the journal, verification of the originality of the work, the authors’ confirmation that the manuscript is currently submitted only to this journal, declarations and ethical statements, suggested potential reviewers, and contact information of the corresponding author of the submitted work ( 5 , 6 ). Other manuscript characteristics, including the length and number of tables and figures, can also be indicated. If the manuscript belongs to a special issue or is being submitted upon an official invitation from the journal’s editorial office, it should also be addressed. The main contents of the first cover letter are described in Table 1 .

VariablesValues
Editor (s)’ name and position (in bold print); Date of submission (MM-DD-YYYY)
First paragraph (manuscript’s characteristics)Title of the manuscript (in bold print); Type of the manuscript, Name of the journal; Address if the manuscript belongs to a special issue or is being submitted upon an invitation; The length of the manuscript, the number of tables and figures
Second paragraphThe line of research presented in the manuscript; Novelty/significance/implication statement (s) (i.e., brief explanation regarding the research background of the study, the question answered in the study, the importance of study findings, and the take-home-message); Address to potential readers (i.e., indicating why the journal’s readers would be interested in this study)
Third paragraph (declarations/obligatory statements)Author agreement statement; Conflict of interest statement; Funding source declaration; Ethical standards or other statements required by the journal; Permission statement (if the manuscript contains previously published materials); Statement regarding English native editing (if applicable); Potential reviewers
“Sincerely,” or “Best regards,” or …; Sign of corresponding author (s) (with full name and academic position); Contact information of corresponding author and co-authors (if required by the journal) (i.e., affiliation, postal address, email address)

The most critical element of a cover letter is a “statement of novelty/significance/implication.” The authors are advised to carefully write a brief and concise description of their work’s impact toward communicating its significance ( 6 ). The authors are strongly advised not to copy the abstract into the cover letter and instead explain in their own words the significance of the work and the reason for submitting it to the journal ( 11 ). If this information is lacking, the editors may rely on the reviewers who may not appreciate the significance of the work and just focus on the technical issues rather than the scientific value of the work ( 5 ). Providing a clear and robust statement of novelty and significance would be more critical for editors and potential reviewers with diverse and interdisciplinary backgrounds ( 6 ).

The statements are expected to answer the following questions: (1) why is the work important? (e.g., emphasizing a new measurement, a new diagnostic method or criterion, a newly discovered biological process); and (2) how does the work advance current knowledge in the field? The best approach to answer this question is by describing the current state of knowledge in the field and clarifying how the work provides an added value by answering a previously unanswered question, finding the solution to a problem, or improving existing methods ( 5 ). Checking the recently published papers on similar topics in the journal provides new insights for the authors to clarify in the cover letter as to how the manuscript follows the publication trends of the journal and will add something new that would be relevant to the trend ( 12 ).

The cover letter is also expected to emphasize why the manuscript will attract the journal’s readers ( 5 ). The authors also need to consider the journal’s Aims and Scope to underscore how the manuscript would fit within the journal’s scope and attract potential readers ( 13 ). Instead of stating simply that the manuscript is “of interest to the field” or “novel,” the authors should address specific aspects of the journal’s Aims and Scope statement, e.g., “We believe that this manuscript is appropriate for publication by [journal name] since it… [reference to the journal’s aims and scope] ( 11 ).

For a review, opinion, or a trends paper, emphasizing the timeline and novelty is needed, as stated by Sacristán, the editor of trends in molecular medicine: “The synthesis and conceptual advance should be particularly stated in terms of what is new and has been trending in the field for the last one to five years”. She also recommends that the authors need to provide a future perspective beyond the main take-home message of the manuscript for a trends paper and take a strong and novel stance on a hypothesis or idea for a cover letter of an opinion manuscript ( 14 ).

The cover letter must contain some predefined statements, including the “author agreement” statement ( 13 ). An “author agreement” is a statement to confirm that “all authors have read and approved the final version of the manuscript being submitted” ( 8 ). Furthermore, “the authors warrant that the manuscript is their original work, has not received prior publication and is not under consideration for publication elsewhere” ( 8 ). Some journals may request the corresponding author to confirm that he/she will take responsibility for informing co-authors of editorial decisions, reviews received, and any changes or revisions made; additionally, the editor (s) should be informed about any closely related manuscript (s) simultaneously submitted for consideration to the same or another journal ( 15 ). The authors also should declare if any part of the submitted work has been previously published elsewhere, even as an abstract ( 16 ); e.g., “there is some overlap in the content of the introduction section, which we have noted in the text”.

Depending on the journal’s policy, other statements, including “conflict of interest statement”, “funding source declarations”, and “permission note”, may also be required to be included in the cover letter ( 8 , 11 ). As indicated by Elsevier, a conflict of interest statement, known as a disclosure statement, is a declaration from the author that “there is no financial/personal interest or belief that could affect their objectivity”. The publisher emphasizes that the authors should declare and state the potential conflict’s source and nature in cases where a conflict of interest exists. A funding source declaration is defined by the publisher as “a declaration of any funding or research grants (and their sources) received in the course of study, research or assembly of the manuscript”. Elsevier also defines the permission note as a statement that declares that “permission has been received to use any material in the manuscript such as a figure, which is not original content” ( 8 , 17 ). Other statements like “Statement of English native editing” may also be added.

Furthermore, informing the editor (s) regarding any information that will support the submission (e.g., original or confirmatory data, supplementary materials, relevance, topicality) can be helpful ( 8 ). Other operational information, typically provided within checkboxes of the journal’s submission system, is not required to be included in the cover letter ( 5 ).

3.2. Second Cover Letter

The second cover letter, which accompanies the revised version of the manuscript, must be a model of clarity and must address every issue posed by the editor and reviewers ( 10 ). If the revised manuscript is sent for the second round of peer-review, the reviewer (s) will see the letter. The content of the header and footer sections of the revised letter is similar to that of the submitted cover letter. The letter should be directed to the editor as addressed in the first letter unless the authors are informed that a new editor will process the revised version ( 10 ). The first paragraph should start with an “expression of polite gratitude”, e.g., “we would like to thank you for the opportunity to revise and resubmit our manuscript.” The “manuscript ID” or “identification number,” usually assigned by the journal in the first submission, should be addressed in the first paragraph ( 10 ).

The second paragraph usually “signals attention to the reviewers’ comments” by providing an explicit reference to the comments made by the reviewers and the editor. Furthermore, it may contain a positive statement regarding the results, methodology, conclusions, etc., in which case the authors need to acknowledge reviews’ insights ( 10 , 18 ). For example, “We sincerely appreciate all the valuable comments and suggestions made, which helped us improve the revised version of our manuscript” or “we found the reviewers’ comments helpful in guiding us to revise the manuscript.” Such statements will help the authors in creating a polite, formal tone throughout the letter. The paragraph should be followed by providing the editor with a roadmap or a summary of the revisions, addressing “the response to comments attachment.” A point-by-point response to the specific comments of the reviewers must be provided. If the authors disagree with a point raised by a reviewer, a rebuttal or counterstatement may be in order. A scientific and polite approach should spell out why the authors disagree, never losing sight of the reviewer’s opinion ( 19 ).

The footer section (closing salutation) of the letter returns to polite formalities, using statements like “we hope that the revised version of our manuscript is now acceptable to the reviewers, and suitable for publication in the [name of journal], we look forward to hearing from you at your earliest convenience” ( 10 ).

4. Organization

Although it is not a rule, the cover letter’s content can be organized within a cover letter header (opening salutation), three main paragraphs (the body of cover letter), and a cover letter footer (closing salutation), as described in Table 1 .

The cover letter should be initiated by addressing the editor (s) and the target journal; however, the author’s affiliation and contact information may also be included at the top of page ( 4 ). The name of the editor (s) can be easily found on the journal’s information page. If it is known, the authors must address the editor who will receive the manuscript and handle the peer-review process ( 13 ). If there are several co-editors, the person the author feels has the most appropriate background, and specialty of the topic should be addressed. In cases where such information is lacking, authors can mention all editors by name or address the letter to “dear editors” ( 12 ); however, it has been recommended to avoid writing “dear editor” ( 16 ). Also, the submission date and the journal’s name where the manuscript will be submitted are required ( 13 ).

In the first paragraph of the cover letter body, to introduce the submitted work, the title and the type of manuscript, authors’ name, journal name, and manuscript length are presented ( 4 ). In addition, it is mentioned that whether the manuscript is submitted upon an invitation or belongs to a special issue. The importance of the study, including novelty, potential implications, and its take-home message, are addressed in the second paragraph of the cover letter body. In addition, it is explained why the work would be attractive for journal readers. The third paragraph of the cover letter body includes some statements including authorship agreement, conflicts of interest, funding source, and ethical considerations. If required, potential reviewers are also suggested here.

Within the closing salutation, the authors can appreciate the editor for taking the time to read the cover letter and considering the submitted work for potential publication.

5. Some Practical Tips: The Length, and Dos and Don’ts

The authors need to spend plenty of time crafting their cover letters. They are advised to avoid too many details and keep it within one page (less than 200 words), like an introduction or a brief overview ( 4 , 11 ). The authors should check the guide for authors and cover letter suggestions provided by the journal, including all the requirements, e.g., specific disclosures, statements, and potential reviewers. Some publishers (e.g., Springer, https://www.springer.com/gp/authors-editors/journal-author/cover-letters/1398, Taylor & Francis, https://authorservices.taylorandfrancis.com/publishing-your-research/making-your submission/writing-a-journal-article-cover-letter/) provide sample cover letters that the authors can use. Figure 1 provides a sample for a cover letter.

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If the authors address previously published papers in the cover letter, then appropriate citation should be considered. The authors should carefully check the letter for any spelling and grammatical errors ( 11 , 20 ). They should make sure that they correctly spell the name of the journal’s editor (s) ( 4 ). Being careless regarding the editor’s name or the change of a journal’s name in a cover letter of a resubmitted manuscript, can be embarrassing and make a bad impression ( 4 ). It is suggested that the cover letter be written on the authors’ institutional letterhead to display professionalism and reliability ( 20 , 21 ).

5.2. Don’ts

When authors suggest a number of potential reviewers, they should avoid suggesting their friends and colleagues, as this would be viewed as a conflict of interest. Collaborators whom the authors have published with in the past five years should not be suggested either; an editor may easily be informed of such associations by a quick search of PubMed or other databases ( 22 ). The authors should avoid using complex sentence structures, jargon, and acronyms and keep the text straightforward and easy to read ( 11 , 20 ). The authors should also avoid including unrelated personal information or glorifying their past research papers or any of their academic accolades ( 20 ). They must not be rude towards the editors or complement the editor’s accomplishments ( 4 ). The novelty statement should not exaggerate or overstate the findings of the work; furthermore, any conclusion stated should be completely supported by the data provided in the manuscript ( 23 ). Finally, authors are recommended not to write a generic cover letter that could be used for any manuscript and could be sent to any journal ( 21 ).

6. Conclusion

In summary, a cover letter should highlight the novelty, importance, take-home message, and goodness-of-fit of the manuscript to the journal. These are critical information that can persuade an editor that the submitted work merits publication consideration in the journal. The cover letter should not be general but should be custom-written for the target journal. Although the submitted manuscript may usually pass through the peer-review process and get published regardless of the cover letter, a well-written, informative, and concise cover letter increases the chance of gaining acceptance.

Authors' Contribution: Study concept and design, Zahra Bahadoran and Asghar Ghasemi; Drafting of the manuscript, Zahra Bahadoran, Parvin Mirmiran, and Asghar Ghasemi; Critical revision of the manuscript for important intellectual content, Khosrow Kashfi and Parvin Mirmiran.

Conflict of Interests: The authors have no conflict of interest.

Funding/Support: This study was supported by the Shahid Beheshti University of Medical Sciences (grant number 28127).

Professional Biomedical Engineer Cover Letter Examples for 2024

Your biomedical engineer cover letter must first highlight your proficiency in blending the principles of engineering with biomedical sciences. Show how your skills have contributed to tangible healthcare solutions. In your second paragraph, demonstrate your ability to work collaboratively with medical staff and researchers. Your cover letter should reflect a deep understanding of patient-centered design and innovation.

Cover Letter Guide

Biomedical Engineer Cover Letter Sample

Cover Letter Format

Cover Letter Salutation

Cover Letter Introduction

Cover Letter Body

Cover Letter Closing

No Experience Biomedical Engineer Cover Letter

Key Takeaways

Biomedical Engineer cover letter

Embarking on your job search, you've likely discovered the need for a standout biomedical engineer cover letter—a daunting task even for seasoned pros. Unlike your resume, this is your chance to weave a compelling narrative around your proudest professional achievement. Remember, formal doesn't have to mean stuffed with clichés! Keep it concise, limit it to one page, and captivate your potential employer by showing the unique value only you can bring to their team.

  • Making excellent use of job-winning real-life professional cover letters;
  • Writing the first paragraphs of your biomedical engineer cover letter to get attention and connect with the recruiters - immediately;
  • Single out your most noteworthy achievement (even if it's outside your career);
  • Get a better understanding of what you must include in your biomedical engineer cover letter to land the job.

Let the power of Enhancv's AI work for you: create your biomedical engineer cover letter by uploading your resume.

If the biomedical engineer isn't exactly the one you're looking for we have a plethora of cover letter examples for jobs like this one:

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Biomedical Engineer cover letter example

PETER CONNOLLY

Boulder, CO

+1-(234)-555-1234

[email protected]

  • Highlighting relevant past experience: The cover letter does a good job of detailing specific achievements, such as leading a cross-functional initiative that increased team efficiency, which directly relates to the demands of a biomedical engineering role at Taylor Labs Inc.
  • Emphasizing improvements and results: Mentioning the implementation of improved testing techniques and the subsequent increase in accuracy and reliability of biomedical devices demonstrates a successful application of skills and professional impact.
  • Expressing alignment with company values: The cover letter addresses the candidate's awareness of Taylor Labs' commitment to innovation in regenerative medicine, which suggests a good cultural and professional fit for the role of a Sr. Biomedical Engineer.

Standard formatting for your biomedical engineer cover letter

Structure your biomedical engineer cover letter, following industry-leading advice, to include:

  • Header - with your name, the role you're applying for, the date, and contact details;
  • Greeting - make sure it's personalized to the organization;
  • Introduction paragraph - no more than two sentences;
  • Body paragraph - answering why you're the best candidate for the role;
  • Closing paragraph - ending with a promise or a call to action;
  • Signature - now that's optional.

Set up your biomedical engineer cover letter for success with our templates that are all single-spaced and have a one-inch margin all around.

Use the same font for your biomedical engineer cover as the one in your resume (remember to select a modern, Applicant Tracker System or ATS favorites, like Raleway, Volkhov, or Chivo instead of the worn-out Times New Roman).

Speaking of the ATS, did you know that it doesn't scan or assess your cover letter? This document is solely for the recruiters.

Our builder allows you to export your biomedical engineer cover letter in the best format out there: that is, PDF (this format keeps your information intact).

The top sections on a biomedical engineer cover letter

  • Header: Include contact information, date, and the employer's details to ensure your cover letter appears professional and to make it easy for the recruiter to identify and reach out to you.
  • Opening Greeting: Address the hiring manager or committee by name if possible, as personalizing the letter can help build an initial rapport and shows attention to detail.
  • Introduction: Mention your educational background in biomedical engineering and briefly highlight your enthusiasm for the role and the company, to immediately establish your relevance to the job.
  • Body (Professional Experience): Elaborate on your specific biomedical engineering experiences and relevant projects, emphasizing your technical skills, research, design experience, and knowledge of regulatory standards, to showcase your suitability for the role.
  • Closing and Call to Action: Express your desire for an interview, reiterate your passion for biomedical engineering, and thank the reader for their time, leaving a positive and proactive final impression.

Key qualities recruiters search for in a candidate’s cover letter

  • Proficiency in biomedical devices and systems: Demonstrates an understanding of how medical equipment operates, which is crucial for developing and improving medical technology.
  • Strong analytical and problem-solving skills: Essential for diagnosing problems with biomedical equipment and creating innovative solutions.
  • Interdisciplinary knowledge: Knowledge of biology, medicine, and engineering principles is key to ensuring that biomedical solutions are effective and safe for patient use.
  • Experience with regulatory standards: Understanding of FDA regulations and ISO standards ensures that new products comply with necessary legal and quality requirements.
  • Exceptional communication skills: Ability to clearly communicate complex technical information to non-technical stakeholders, including healthcare professionals.
  • Background in clinical environments: Experience in clinical settings provides insight into the practical needs and challenges faced by healthcare providers, leading to more user-friendly designs.

How to start your biomedical engineer cover letter: with a greeting, of course

Have you ever considered just how powerful a personalized salutation can be?

We sure have news for you! Your biomedical engineer cover letter should start with the right salutation to recruiters, nurturing a sense of respect and individuality.

Greet recruiters by using their first name (e.g. "Dear Tom" or "Dear Patricia") if you've previously established contact with them.

Otherwise, opt out for the less familiar, "Dear Ms. Peaches" or "Dear Ms Kelsey", if you've found the recruiter's name on LinkedIn or a corporate website.

"To whom it may concern" is never a good option, as it creates a sense that you've been sending out your biomedical engineer cover letter to anyone. Instead, use "Dear HR team" or "Dear (company name) recruiter" for a feeling of exclusivity.

List of salutations you can use

  • Dear Hiring Manager,
  • Dear [First Name] [Last Name],
  • Dear Dr. [Last Name],
  • Dear Mr./Ms. [Last Name],
  • Dear Search Committee,
  • Dear Recruiting Team,

Introducing your profile to catch recruiters' attention in no more than two sentences

The introduction of your biomedical engineer cover letter is a whole Catch 22 .

You have an allocated space of no more than just a paragraph (of up to two sentences). With your introduction, you have to stand out and show why you're the best candidate out there.

Set out on a journey with your biomedical engineer cover letter by focusing on why you're passionate about the job. Match your personal skills and interests to the role.

Another option for your biomedical engineer cover letter introduction is to show you're the ideal candidate. Write about how your achievements and skills are precisely what the company is looking for.

However you decide to start your biomedical engineer cover letter, always remember to write about the value you'd bring about. Making it both tangible (with your metrics of success) and highly sought out.

How to select your best achievement for the middle, or the biomedical engineer cover letter body

You probably feel exhausted by this point in your application: you've dived into all the details of your success and skills in your biomedical engineer resume.

What else can you include in your biomedical engineer cover letter body ?

Well, for starters, the next three to six paragraphs should show you further value as a professional. Or, why should recruiters choose you?

Think back on a noteworthy achievement that answers key job requirements and dive deep.

Structure your biomedical engineer cover letter middle as you'd a story: following chronological logic and highlighting outcomes, thanks to skills.

At the end of the day, you'd want recruiters to be able to see you as the best candidate for the role and understand more about who you are and what makes your success unique (and valuable to the role).

Closing paragraph basics: choose between a promise and a call to action

You've done all the hard work - congratulations! You've almost reached the end of your biomedical engineer cover letter .

But how do you ensure recruiters, who have read your application this far, remember you?

Most biomedical engineer professionals end their cover letter with a promise - hinting at their potential and what they plan on achieving if they're hired.

Another option would be to include a call for follow-up, where you remind recruiters that you're very interested in the opportunity (and look forward to hearing from them, soon).

Choose to close your biomedical engineer cover letter in the way that best fits your personality.

No experience biomedical engineer cover letter: making the most out of your profile

Candidates who happen to have no professional experience use their biomedical engineer cover letter to stand out.

Instead of focusing on a professional achievement, aim to quantify all the relevant, transferrable skills from your life experience.

Once again, the best practice to do so would be to select an accomplishment - from your whole career history.

Another option would be to plan out your career goals and objectives: how do you see yourself growing, as a professional, in the next five years, thanks to this opportunity?

Be precise and concise about your dreams, and align them with the company vision.

Key takeaways

Your biomedical engineer cover letter is your best shot at standing out by showing your motivation and the unique skills you'd bring to the job:

  • Chose no more than one achievement, which you'd be talking about in the body of your biomedical engineer cover letter, by focusing on skills and outcomes;
  • Address recruiters with their first or last name, or "Dear Hiring Manager" in your biomedical engineer cover letter greeting;
  • Introduce in no more than two sentences what makes your profile unique (perhaps it's your motivation, enthusiasm, or appreciation of the company you're applying for);
  • Select the same font you have used in your resume (avoid Times New Roman and Arial, as most candidates tend to invest in them);
  • Close your biomedical engineer cover letter with a promise of how you see yourself growing in the company and the benefits you'd bring about.

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Resume Worded   |  Career Strategy

14 biomedical engineer cover letters.

Approved by real hiring managers, these Biomedical Engineer cover letters have been proven to get people hired in 2024. A hiring manager explains why.

Hiring Manager for Biomedical Engineer Roles

Table of contents

  • Biomedical Engineer
  • Senior Biomedical Engineer
  • Associate Biomedical Engineer
  • Alternative introductions for your cover letter
  • Biomedical Engineer resume examples

Biomedical Engineer Cover Letter Example

Why this cover letter works in 2024, highlighting relevant experience.

This sentence effectively highlights the candidate's relevant experience in designing a novel wearable medical device. It showcases their technical skills and ability to lead a team, both of which are important for a biomedical engineering role.

Quantifiable Accomplishment

By providing a specific example of reducing production costs, the candidate demonstrates their ability to make a tangible impact on a company's bottom line. This accomplishment sets them apart from other applicants who may not provide concrete examples of their work.

Expressing Genuine Enthusiasm

This sentence shows the candidate's excitement about the role and their genuine interest in working on projects that have the potential to revolutionize patient care. This enthusiasm can help the candidate stand out from others who may not express as much passion for the industry and role.

Showcasing tangible achievements

Highlighting a specific achievement where you made a significant impact is a fantastic way to grab my attention. In this case, you've reduced patient recovery time by 20% - that's impressive. It's not just about listing duties here, it's about the outcomes. This tells me you're action-oriented and focused on results, which is exactly what we need in our team.

Passion for the role

I love that you've explicitly expressed your passion for creating and optimizing biomedical devices. It's clear that you understand the field and genuinely care about improving patient outcomes. This tells me that you're not just looking for any job, but specifically a role where you can use your skills to make a real difference.

Aligning with the company mission

By expressing your eagerness to contribute to the company's mission, you're showing me that you've taken time to understand our values and are motivated to help us achieve our goals. This demonstrates a level of engagement and commitment that sets you apart.

Showcasing Impact Through Tangible Results

By detailing a specific project where you led to the development of a successful product and its impact - a drop in patient readmissions - you've given a clear understanding of your ability to make a difference. It's like saying, "Here's what I've done in the past, and I can do it again for you."

Emphasizing Soft Skills Alongside Technical Expertise

Stating your desire to bring innovation and empathy to the company speaks volumes about you. It's not just about designing devices, but also understanding the patients who will use them. This shows your ability to balance technical skills with a people-first approach, which is critical in healthcare.

Aligning Personal Interest with Job Role

By expressing your excitement about designing devices that improve quality of life, you've made your passion for the role evident. This shows that you're not only qualified for the job, but also genuinely interested in what you'll be doing, which can be a strong motivator.

Understanding Company Culture

By acknowledging the culture of continuous learning and innovation, you're showing that you've done your homework about the company. This tells me that you're not only interested in the job but also the environment where you'll be working, which is important for fitting in and thriving.

Asserting Your Value

Asserting that your background in developing user-focused medical devices and your passion would make you a valuable addition to the team shows confidence in your ability to contribute. It's great to see this kind of self-assurance - it tells me that you believe in what you can bring to the table.

Show your passion for biomedical engineering

Sharing why you're drawn to a company's mission shows me you care about more than just a job. It makes me believe you'll bring enthusiasm to our projects.

Highlight your impact on patient care

Talking about how your work improved patient outcomes tells me you're focused on what matters most in our field: helping people.

Stress collaboration in biomedical projects

Mentioning your ability to work with different groups makes you stand out as a team player who can contribute to complex projects.

Connect with the company's mission

When you express a connection to our mission, it suggests you'll be committed and driven in your role here.

Express eagerness to contribute

Closing by looking forward to discussing your role shows me you're proactive and ready to make a difference.

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Match your passion with the company's groundbreaking work

Starting your letter with a direct acknowledgment of the company’s achievements in the biomedical field instantly aligns your interests with ours, making you a compelling candidate right off the bat.

Emphasize collaboration and technical expertise

By highlighting your history of delivering results through teamwork and technical know-how, you're telling me that you not only have the skills but also understand the importance of collaboration in our field.

Share significant achievements in biomedical engineering

Detailing your role in bringing a cutting-edge product to market, especially one that has achieved considerable success, positions you as a high-impact player in our team, capable of leading projects that make a difference.

Connect with the company’s mission on a personal level

Your personal connection to our mission of improving lives around the world adds depth to your application, showing me that you're here for reasons that go beyond the job itself.

Invite further discussion on your potential contributions

Closing with an invitation to discuss how you can contribute to our success not only shows your confidence but also your readiness to take on challenges and drive forward our company’s objectives.

Show genuine interest in the company's goals like Medtronic's mission. This shows you're not just looking for any job, but you want to be part of their specific journey.

Show your biomedical engineering impact

Describing a specific project where you led a team and achieved significant results demonstrates your capability to handle responsibility and make a tangible difference in the field.

Highlight achievements in biomedical research funding

Mentioning your success in securing grant funding showcases your ability to support important research initiatives, a valuable skill for any biomedical engineering role.

Express enthusiasm for the role's potential

Sharing your excitement about working on advanced medical devices at Medtronic reveals your passion for the field and eagerness to contribute to meaningful projects.

Close with a forward-looking statement

Ending your letter by expressing hope for a discussion about your fit for the role leaves a positive, proactive impression on the hiring manager.

Senior Biomedical Engineer Cover Letter Example

Highlighting leadership and results.

Mentioning that you've led a team and developed FDA-approved medical devices is fantastic, but you didn't stop there. You went on to quantify your success by stating that your efforts reduced time-to-market by 15%. This gives me a clear picture of your capabilities and your potential impact on our team. It also tells me you're a leader who's able to drive results.

Expressing confidence

Confidence can be a deal-breaker. By stating that you're confident your blend of skills and passion would make you a valuable addition to the team, you're essentially telling me you're ready to hit the ground running. Just ensure your confidence doesn't come off as arrogance. It's a fine line to tread, but you've done it well here.

Highlighting Past Achievements

By pinpointing a particular project where you developed a diagnostic tool with a high accuracy rate, you're highlighting your capability to create impactful solutions. It's a subtle way of saying, "Look at what I've achieved, and imagine what I can do for you."

Demonstrating Initiative and Leadership

Establishing an innovation hub and accelerating projects shows initiative and leadership skills. It's the kind of proactive action employers love to see, especially in senior roles. You're showing them that you're not just a doer, but also a mover and shaker.

Expressing Desire to Foster Innovation

Expressing your passion for fostering a culture of innovation and excellence reveals your leadership style. It shows that you're committed to not only achieving success but also creating an environment where innovation thrives. This is something that can be infectious within a team.

Connecting Your Aspirations with the Company's Goals

Stating that the company's commitment to tackling health issues resonates with your professional journey and aspirations creates a strong connection. It shows that you're not just looking for any job, but a role that aligns with what you care about. This can be a powerful motivator for you and is appealing to employers.

Expressing Eagerness to Contribute

By stating you're eager to bring your expertise and passion to the company, you're showing determination to make a meaningful contribution. It's like saying, "I'm not here to just do a job, I'm here to make a difference," which is what every employer wants to hear.

Share a defining moment in your career

Telling a story about what sparked your interest in biomedical engineering makes your cover letter memorable and personal.

Showcase your achievements in device development

Detailing your successes, especially ones with significant outcomes, demonstrates your ability to lead projects that deliver results.

Emphasize leadership in team projects

Highlighting your leadership skills in cross-functional teams assures me you can handle the responsibilities of a senior role.

Align with the company's vision for patient care

Showing your enthusiasm for our specific areas of innovation indicates you're a good fit for our team's direction.

Invite further discussion on your potential contribution

Ending on a note of openness to discuss your fit for the role signals your confidence in how you can add value to our mission.

Highlight your experience and respect for the company

When you share your long experience and admiration for the company, it shows you are not just looking for any job but are invested in this specific role.

Show your teamwork in biomedical engineering projects

Detailing how you've worked closely with healthcare professionals underlines your ability to collaborate effectively, a crucial skill in developing products that meet real-world needs.

Discuss previous significant projects

Talking about your role in developing impactful medical devices demonstrates your capacity to contribute significantly to future projects.

Emphasize your regulatory awareness

By highlighting your work with quality and regulatory teams, you reassure the employer of your understanding of the critical compliance landscape in biomedical engineering.

Express eagerness for further discussion

Closing with a note of thanks and a forward-looking statement invites a dialogue, showing your genuine interest in the position.

Share a personal connection to biomedical engineering

Telling a story about what drew you to the field demonstrates your deep personal commitment and passion, making you a more memorable candidate.

Quantify your achievements in product development

By listing specific successes, like reducing recovery time and manufacturing defects, you provide clear evidence of your ability to contribute valuable innovations to the company.

Lead with your leadership in cutting-edge technology

Discussing your current role in developing a groundbreaking neural implant positions you as a leader in the industry, ready to bring your expertise to new challenges.

Emphasize your excitement for innovation

Expressing eagerness to work on specific technologies like the WATCHMAN FLX™ shows you are knowledgeable and passionate about the field's latest advancements.

End with a strong, eager closing

Closing your letter by expressing eagerness to contribute to the company's mission reinforces your genuine interest in the role and the company's goals.

Associate Biomedical Engineer Cover Letter Example

Connect your passion with the company's mission.

Sharing your fascination with how medical devices change lives shows that your interests align perfectly with the company's goals. This approach tells me you're not just looking for any job – you want this job.

Demonstrate hands-on experience in biomedical engineering

Talking about your direct experience in medical device design not only showcases your skills but also that you've successfully applied them in real-world situations. It’s essential for me to see that you’ve not just learned, but also done.

Highlight teamwork in biomedical projects

Mentioning your ability to work well in a team setting, especially in a collaborative environment like ours, reassures me that you’ll fit into our workplace culture and contribute effectively to our projects.

Show your motivation for improving patient outcomes

Expressing your draw to the company’s focus on patient outcomes through innovative medical devices tells me you’re driven by purpose, not just tasks, which is crucial for long-term success here.

Express eagerness to contribute to the company's mission

Your willingness to discuss how your skills and passion for biomedical engineering can support our mission makes your cover letter not just an application, but a conversation starter.

Start with a personal story

A personal anecdote about what drew you to biomedical engineering makes your cover letter memorable and shows your passion for the field.

Highlight your research and innovation

Mentioning your work on a novel biomaterial demonstrates your ability to contribute to cutting-edge research and innovation in biomedical engineering.

Showcase diverse experiences

Discussing internships at different companies illustrates your practical experience and adaptability, important traits for an associate biomedical engineer.

Demonstrate problem-solving skills

Explaining how you improved manufacturing processes showcases your analytical and problem-solving skills, crucial for efficiency and innovation in medical device development.

Invite further conversation

Concluding with a statement that looks forward to discussing your qualifications further shows politeness and openness for dialogue, setting the stage for an interview.

Show your admiration for the company’s work

Expressing genuine respect for the company’s achievements shows that your interest is not just in any job, but in making a real impact in an area you care deeply about. It helps me see you're someone who will be passionate about our projects.

Highlight your innovative project experience

When you detail a specific project where you achieved significant results, it shows me you have hands-on experience and can bring valuable skills to our team. It's particularly impressive when these projects align with our field of work.

Demonstrate your passion for translating research into solutions

Illustrating how your experiences have not only honed your technical abilities but also ignited a drive to solve real-world problems tells me you’re not just interested in theory. You're someone who wants to see tangible results from your work.

Connect with the company’s values

Mentioning specific aspects of our culture that appeal to you makes your application feel personal. It suggests that you’ve done your homework and see yourself as a good fit, not just in terms of skills but also in sharing our commitment to innovation.

Express eagerness to contribute to the mission

Closing your letter by directly stating your desire to help advance our mission reinforces your genuine interest in the role and our goals. It’s a strong end note that leaves a lasting impression of your enthusiasm and potential contribution.

Alternative Introductions

If you're struggling to start your cover letter, here are 6 different variations that have worked for others, along with why they worked. Use them as inspiration for your introductory paragraph.

Cover Letters For Jobs Similar To Biomedical Engineer Roles

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biomedical phd cover letter

Thank you for the checklist! I realized I was making so many mistakes on my resume that I've now fixed. I'm much more confident in my resume now.

biomedical phd cover letter

Clinical psychology

Psychotherapy, personality, cover letter for a biomedical engineer (5 samples).

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Samples of biomedical engineer cover letters

To get a biomedical engineer position, you need a well-written cover letter that showcases your passion for and dedication to the industry. When writing a cover letter for a biomedical engineer, these are some of the essential things to include in your letter:

I am submitting my resume for the position of Biomedical Engineer. With a bachelor’s degree in biomedical engineering from one of the country’s top biomedical engineering programs, two years of experience gained through a rigorous internship, excellent analytical, design, and engineering skills and a knack for working with cross-functional teams, I believe I’d be a valuable asset to HeartTech.

My professional experience includes maintaining, updating and repairing biomedical equipment, designing new and groundbreaking biomedical equipment, train medical personnel to properly use biomedical equipment and working with scientists, healthcare professionals and fellow engineers to design and realize the best possible products. Over the course of my career, I have learned that being able to communicate and truly understand the needs of patients is just as important to success in the field of biomedical engineering as a passion for biology and an analytical mindset.

Earned a bachelor’s degree in biomedical engineering from the University of California, San Diego

Assisted in the training of dozens of Spitzer Health personnel in the proper use of equipment

I hope to be able to use my skills and experience to create new and life-saving biomedical equipment as a part of the HeartTech team.

Hazel Schaffer

I am writing to apply for the Biomedical Engineer position that was recently advertised on your company website. I am confident that I have the skills and qualifications that you are looking for, and I am eager to put my experience to work for your team.

As a biomedical engineer with three years of experience in the industry, I have a deep understanding of the principles of biomedical engineering and the ability to apply them in a practical setting. I have experience in designing and developing medical devices, conducting clinical trials, and working with patients. I am also well-versed in the latest software and technologies used in the field.

Most importantly, I have a passion for helping others. I take great pride in my work, and I am always looking for ways to improve the quality of life for patients. I am confident that I can be a valuable asset to your team, and I look forward to the opportunity to discuss this further with you.

Thank you for your time and consideration. I look forward to hearing from you soon.”

Frequently Asked Questions:

How do i write a career objective for biomedical engineering, what are your professional career objectives examples.

“Seeking an entry-level position to begin my career in a high-level professional environment. To secure employment with a reputable company, where I can utilize my skills and business studies background to the maximum. Seeking a challenging career with an MNC.”

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Graduate Intern - Biomedical Ethics- Temporary

  • Rochester, MN

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The primary purpose of the Graduate Internship is to provide an intern with relevant field experiences in their chosen field of study. One or more mentors will be assigned to the intern to provide instruction, guidance and to assess performance. The intern is responsible for observing the functions and processes of the assigned work unit. In addition, the intern may be given selected work assignments to reinforce the learning experience, to assess the performance levels and to provide benefit to the work unit. The intern will be responsible for completing all internship-related assignments and reports for both Mayo and the participating educational facility. The duration and timing of the internship will be arranged with the intern.

In addition, Biomedical Ethics interns will participate in a biomedical ethics summer curriculum, which includes educational sessions on bioethics research methods and lunch meetings with members of the program faculty. 

This position has an anticipated start date of May 27 or June 2, and an anticipated end date of August 8 or August 15, 2025. 

Applications must be received by January 17, 2025, 11:59pm CST, and must include the following items:

•              A cover letter describing your career goals and how biomedical ethics research relates to those goals.

•              A resume/CV that includes your major and relevant courses, honors, and experiences.

•              A 5-10-page writing sample (such as a course paper), preferably on a topic related to biomedical ethics.

•              A current, unofficial college transcript.

•              Two letters of recommendation from a professor or research mentor. Address letters to Dr. Richard Sharp, Program Director. Letters should be emailed directly by the professor/mentor to [email protected]

Top applicants will be invited to participate in a brief phone interview to discuss specific skills and areas of interest. Final decisions will be made in part based on applicants' interests and availability of appropriate mentors. 

Note: if you are unable to spend a full 10 weeks in Rochester, Minnesota, or are interested in opportunities in our Arizona or Florida campuses, please describe this in your cover letter. Remote or hybrid positions might be possible for well-qualified applicants.

Qualifications : The incumbent must be enrolled in a masters or graduate degree program from a college or university. 

Applicants who do include the required items listed above will not be considered. 

Must have authorization to work and remain in the United States, without necessity for Mayo Clinic sponsorship now, or in the future (for example, be a U.S. citizen, national, or permanent resident, refugee or asylee).

This position will require a MN background check 

Additional Qualifications: 

Successful applicants will be:

•              committed to pursuing a career in which they will engage topics in biomedical ethics

•              able to work independently

•              proficient in written and verbal communication

•              highly motivated to learn new research methods

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Part 1. Overview Information

National Institutes of Health ( NIH )

Office of AIDS Research ( OAR )

National Institute on Alcohol Abuse and Alcoholism ( NIAAA )

Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD )

National Institute of Mental Health ( NIMH )

National Cancer Institute ( NCI )

R01 Research Project Grant

  • April 4, 2024  - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084 .
  • August 31, 2022 - Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice  NOT-OD-22-198 .
  • August 5, 2022 - Implementation Details for the NIH Data Management and Sharing Policy. See Notice  NOT-OD-22-189 .

See Part 2, Section III. 3. Additional Information on Eligibility.

The purpose of this Notice of Funding Opportunity (NOFO) is to support research projects under Phase 3 of the U.S.-South Africa Program for Collaborative Biomedical Research.  Research areas supported under this program include HIV/AIDS, HIV/AIDS co-morbidities and co-infections, HIV/AIDS-associated implementation science, and HIV/AIDS-associated data science. The hallmark of the U.S.-South Africa program is the development of collaborative partnerships between South African investigators and United States (U.S.) investigators. Through international collaboration, this research will advance scientific discoveries, promote sharing of technologies and approaches, and serve local public health needs and priorities in support of global HIV/AIDS research.

30 days prior to the application due date.

Application Due Dates Review and Award Cycles
New Renewal / Resubmission / Revision (as allowed) AIDS - New/Renewal/Resubmission/Revision, as allowed Scientific Merit Review Advisory Council Review Earliest Start Date
Not Applicable Not Applicable March 12, 2025 July 2025 October 2025 December 2025

All applications are due by 5:00 PM local time of applicant organization. 

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Not Applicable

It is critical that applicants follow the instructions in the Research (R) Instructions in the  How to Apply - Application Guide , except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts ).

Conformance to all requirements (both in the Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review.

IMPORTANT: Per NOT-OD-24-086 updated application forms (FORMS-I) will be used for this opportunity. The updated forms are not yet available and will be posted 30 calendar days or more prior to the first application due date. Once posted, you will be able to access the forms using one of the following submission options:

  • An institutional system-to-system (S2S) solution
  • Grants.gov Workspace

Part 2. Full Text of Announcement

Section i. notice of funding opportunity description.

The National Institutes of Health (NIH) of the United States (U.S.) Department of Health and Human Services (HHS) supports international collaborative biomedical research to advance science and expand biomedical knowledge.  Scientific cooperation between the U.S. and the Republic of South Africa was initiated in 1995 and has grown in recent years. Recognizing that enhanced cooperative biomedical research would be of mutual benefit to the U.S. and South Africa, the NIH Director and the President of the South African Medical Research Council (SAMRC) signed a Memorandum of Understanding (MOU) in January 2013 to develop the U.S.-South Africa Program for Collaborative Biomedical Research.  Phase 1 of this program included awards made in response to RFA-AI-14-009 ,  RFA-AI-14-010 , RFA-AI-14-018 , RFA-AI-16-039 , RFA-AI-16-040 , RFA-AI-16-082 , and  RFA-AI-16-083 . Phase 2 of this program included awards made in response to  RFA-AI-19-022 ,  RFA-AI-19-023 ,  RFA-AI-19-024 , and  RFA-AI-19-025 . The NIH and MRC have developed strategic plans for continued collaboration.  Both the NIH and SAMRC have allocated resources to support the third phase of this program.  Phase 3 will solicit applications for research on HIV/AIDS, HIV/AIDS co-morbidities and co-infections, HIV/AIDS-associated implementation science, and HIV/AIDS-associated data science.

The purpose of this Notice of Funding Opportunity (NOFO) is to establish Phase 3 of the U.S.-South Africa Program for Collaborative Biomedical Research.  Research areas supported under this program include HIV/AIDS, HIV/AIDS co-morbidities and co-infections, HIV/AIDS-associated implementation science, and HIV/AIDS-associated data science.

The intent of this NOFO is to foster, stimulate, and/or expand basic, translational, behavioral, and applied research that will advance scientific discovery and engage U.S. and South African researchers working collaboratively in the areas of HIV/AIDS, HIV/AIDS co-morbidities and co-infections, and HIV/AIDS and associated implementation science and data science. Proposed research should reflect the highest possible scientific standards, as well as shared interests, international and local public health needs and priorities, and involve mutually advantageous collaborations among institutions, including participating communities and other partners. U.S. and South African investigators working with their institutions and in collaborative partnership will prepare and submit a single joint application.  Applications must include at least one South African Program Director/Principal Investigator (PD/PI) from an eligible institution from South Africa (the applicant organization) and at least one collaborator from a U.S. institution/organization.

An overarching goal of this bilateral program is to engage scientists in South Africa from historically disadvantaged institutions (HDIs).  Despite tremendous advancements, there remains unequal participation in the national scientific research agenda in South Africa. NIH and SAMRC encourage South African institutions to enhance the participation of researchers from HDIs, including individuals from groups identified as underrepresented in the biomedical, clinical, behavioral, and social sciences. Underrepresented groups in South Africa include African, Coloured and Indian population groups in South Africa.  One of the major tenets of the SAMRC and the South Africa Department of Higher Education and Training is the development of  research capacity .  Transformation is central to the SAMRC’s strategy, especially transformation in the research landscape.

Scientists from South African HDIs and other South African Universities of Technology and/or scientists from the African, Coloured, or Indian population groups are encouraged to work with their institutions to apply as PD/PIs. In addition, and complementary to the proposed research project, applicants are highly encouraged to include in their applications an optional career enhancement partnership for fostering and enhancing research skills and experience of scientists from under-resourced institutions (HDIs and other South African Universities of Technology) that have a demonstrated commitment to biomedical research but have limited resources or experience. The goal is to develop collaborations that will expose scientists from these institutions to rigorous research experiences. Please note, however, that consistent with NIH practice and U.S. federal law, funded programs may not use the race, ethnicity, or sex (including gender identity, sexual orientation, or transgender status) of a prospective researcher as an eligibility or selection criteria. The race, ethnicity, or sex of researchers or prospective researchers will not be considered by NIH in the application review process or when making funding decisions.   

This NOFO encourages  New Investigators and Early Stage Investigators from the U.S. and South Africa to participate in this research program.

Research Objectives

Basic, translational, behavioral, clinical, preventive, data science, implementation, and/or epidemiological research may be proposed under this program.  HIV-related research is encouraged in accordance with the NIH Director's statement describing the  NIH's overarching HIV research priorities , and the accompanying  Guide NOTICE .

Specific Research Areas of interest include:

Reduce Incidence of HIV (Prevention)

  • Understanding HIV transmission dynamics among different populations and age groups, and the geographic distribution of HIV prevalence and incidence.
  • Informing development of new biomedical prevention strategies through understanding host/virus interactions associated with HIV acquisition, establishment of infection and disease progression.
  • Prevention of perinatal HIV-transmission through primary prevention of HIV transmission, improvement in HIV viral suppression during perinatal periods, and enhanced infant prophylaxis and maternal viral suppression through the breastfeeding period.
  • Voluntary medical male circumcision (VMMC) programs and impact in different populations, including culturally competent practices.
  • Effects of maternal HIV and antiretroviral treatment on HIV-exposed uninfected children.
  • HIV prevention among key and priority populations outlined in the  2023-2028 National Strategic Plan for HIV, TB, and Sexually Transmitted Infections (STIs) : adolescents and young people, particularly adolescent girls and young women (AGYW); survivors of sexual/gender-based violence; sex workers and their clients; sexual and gender minority populations; people who use alcohol and/or other substances; and people in prisons and other closed settings.
  • HIV prevention in adolescent/young adult populations, including strategies to achieve high uptake and adherence to pre-exposure prophylaxis (PrEP).
  • The role of food insecurity and nutrition, housing instability, and other social determinants of health in prevention, care, and treatment of HIV/AIDS.
  • Novel strategies to enhance uptake of HIV testing and sustained linkage to care through differentiated service delivery, including community-based approaches, among key and priority populations in South Africa as outlined in the  2023-2028 National Strategic Plan for HIV, TB, and Sexually Transmitted Infections (STIs) .
  • Risk factors, causes and sequelae of genital inflammation and its role in HIV acquisition in women.
  • The potential role of broadly neutralizing antibodies in HIV prevention and treatment.
  • The potential role of long-acting injectable technologies in HIV prevention and treatment.
  • Tailored interventions for key populations.
  • New HIV testing technologies for self-testing and viral load monitoring, and innovative testing strategies.
  • Examination of pathophysiology and direction of effects between mental health and HIV acquisition as well as broader HIV outcomes.
  • Motivations and reasons for age-disparate sexual partnering (>10 years age difference) and its role in HIV acquisition.
  • Strategies that can reduce the impact of stigma, discrimination, gender bias, prejudice, homophobia, and transphobia on HIV prevention, care, and treatment.
  • Strategies that can strengthen demand for HIV services that promote accurate information dissemination and counter disinformation among diverse populations.

Develop Next-Generation HIV Therapies (Treatment and Care Continuum)

  • Best approaches to optimizing durability of antiretroviral therapy (ART) regimens and adherence support.
  • Strategies on testing, linkage, adherence to HIV treatment, and retention in care, including in adolescent/young adult populations and programmatic combinations with contraception, and including use of mobile, digital, and telehealth technologies and platforms.
  • Approaches to monitoring ART treatment, including consequences of long-acting injectable ART.
  • Strategies to improve annual viral load testing rates for people on ART.
  • Optimal programmatic combinations of HIV treatment and contraception.
  • Differentiated care, including adherence clubs and alternate drug delivery.
  • Laboratory-based research utilizing clinical samples collected from observational cohorts or clinical trials to advance testing of diagnostics and/or development of biomarkers applicable to HIV.

Research Toward HIV Cure

  • Research toward a "functional cure" for adult and/or pediatric HIV and elimination of viral reservoirs.
  • Basic research focused on persistent HIV infection and curative strategies.

Address HIV-Associated Co-Morbidities, Co-Infections, and Complications

  • Impact and management of HIV and TB infection, along with strategies that promote the integration and support of combined HIV and TB care, including novel approaches to improve adherence to TB treatment among people with HIV (PWH).
  • Understanding the immune and/or mycobacterial factors associated with TB pathogenesis among PWH, including subclinical TB and/or post-TB cardio-pulmonary disease.
  • Chronic inflammation in treated HIV disease.
  • Approaches to integrate chronic disease and mental health care into HIV/AIDS care services.
  • Basic research focused on the influence of HIV infection on non-communicable diseases in PWH.
  • Discovery, development, and/or testing of diagnostic and/or prognostic biomarkers, including markers of drug resistance, host directed therapies, and vaccines (both preventive and therapeutic) that can improve outcomes for PWH.
  • Epidemiology of cancer in PWH in the era of antiretroviral therapy.
  • Studies identifying biological differences between tumors occurring in PWH and without HIV.
  • Understanding interactions of HIV with human papilloma virus (HPV), human herpes viruses (EBV and HHV-8), hepatitis B and C viruses, herpes simplex virus (HSV) and other oncogenic viral co-infections that lead to increased cancer risks.
  • Studies on pathogenesis and pathobiology of virally associated cancers in PWH.
  • Strategies for optimizing screening, diagnosis, prevention, and treatment of cancer in PWH.
  • Studies on complications and outcomes of treating cancers among PWH.
  • Studies that enhance our understanding of the role stigma plays in accessing cancer screening and care as well as its impact on survivorship in PWH.
  • Studies identifying strategies for optimizing the integration of HIV care with cancer-related screening and treatment delivery.

Behavior, Mental Health, Substance Use, and HIV Risk

  • Integrative approaches to treating and preventing mental health and substance abuse co-morbidities in HIV, especially in women exposed to violence or abuse, and youth.
  • Studies to test novel approaches to integrate screening for mental symptoms or disorders into HIV prevention or care, with referral and linkages to appropriate levels of mental health care in South Africa.
  • Studies on biomarkers to assess the status of mental health, HIV, and other comorbidities.
  • Cost-effectiveness studies to assess economic benefits of the integration of HIV and mental health system approaches.
  • Mechanisms (e.g., neurotoxic, epigenetic) underlying genetic, physiological, environmental, social, cultural, and economic factors and interactions that affect brain function or development and result in neurobehavioral outcomes (e.g., expression of cognitive impairment, coping, adaptation, response to intervention).
  • Evaluation of the interaction among neuropsychiatric co-morbidities in HIV and age-related cognitive, physical, and functional decline; and how this is affected by socio-environmental and other factors.
  • Neurobehavioral sequelae of perinatal and in utero exposure to HIV, other HIV co-infections, and antiretroviral and related treatments.
  • Studies on the relationship between stress and HIV (e.g., 1. investigation of stress-induced immune changes and implications for HIV; 2. impact of stress and HIV on cognitive impairment; 3. psychosocial dynamics impacted by HIV and stress; and 4. implications of stress on HIV reservoirs).
  • Longitudinal outcomes of the co-occurrence of HIV, alcohol and/or other substance use, and other mental health comorbidities (e.g., depression), and associated genetic, epigenetic, neurobiological, and environmental mechanisms.
  • The role of alcohol and/or other substance use in physical and psychological trauma, including gender-based violence and rape.
  • Evaluation of the effectiveness of integrating alcohol and/or harm reduction programs into HIV prevention, treatment and care programs, and their impact on the overall HIV epidemic.
  • Studies on the link between alcohol use and adherence to HIV medication: 1. development of longer-lasting, less toxic medication regimens for PWH who continue to drink; and 2. assessment, reduction, and prevention of related pathophysiology for organ and tissue injury.
  • Evaluation of the effectiveness of health system-based and/or policy-level interventions on HIV-related health outcomes.
  • Studies on the prevalence and correlates of alcohol use among pregnant women with HIV in South Africa and how effective interventions may be disseminated to improve both maternal and fetal outcomes.
  • Studies on the relationship between cognitive performance and alcohol consumption in people with HIV, and the impact on the development and uptake of interventions to prevent or treat HIV/AIDS.

Implementation Science/Data Science

  • Implementation science research to improve the adoption, implementation, and sustainment of evidence-based or evidence-informed HIV prevention and/or care interventions aimed at improving health outcomes in the context of clinical and community settings for pediatric, adolescent, and young adult, and adult populations.
  • Studies designed to enhance HIV prevention providers’ capacity to assist people in high-incidence or priority populations (e.g., via systems, providers, operational tools)
  • Studies of systemic interventions to influence organizational structure, climate, and culture, to promote organizational readiness and capacity for intervention adoption, and implementation with fidelity and effectiveness.
  • Studies to understand the benefit of varying training methodologies (e.g., didactic training, clerkship, on-site mentoring, on-going consultation, internet-based courses) to prepare providers to offer HIV prevention and treatment services.
  • Studies to optimize the implementation (uptake, effectiveness, efficiency) of individual and/or combination prevention evidence-based interventions (e.g., behavioral risk-reduction, voluntary medical male circumcision [VMMC], PrEP, condom provision), designed to maximize the optimal targeting, uptake, coverage, effectiveness, and efficiency of service provision.
  • Studies to optimize the implementation (uptake, effectiveness, efficiency) of individual and/or combination interventions designed to maximize HIV testing, linkage to HIV care, earlier ART initiation, adherence, and engagement HIV testing, which could include advancements in approaches and technologies.
  • Studies of the impact of varying models of differentiated HIV care on HIV care continuum outcomes, which could include studies to evaluate optimal approaches to integrate community care delivery to include HIV prevention, care, and treatment with related services (mental health, substance use disorders, sexually transmitted infections, family planning, prenatal care, malaria, and/or tuberculosis).
  • Studies to test and evaluate implementation of interventions that address social and structural determinants of health and their impact on HIV prevention, testing, treatment initiation, and continuity.
  • Studies designed to enhance understanding of the epidemiologic contexts for targeted interventions (e.g., accurate rates of testing, linkage, initiation and viral suppression that indicates gaps and targets for intervention).
  • Studies of cost and cost-effectiveness of intervention delivery in real-world settings, including the cost-effectiveness of alternative treatments, services, or payment structures for the provision of services
  • Studies to inform the sustainment and/or sustainability of HIV interventions.
  • Comparative effectiveness research focused on understanding factors related to early detection, patient engagement and retention in appropriate alcohol and HIV care and achieving and maintaining optimal treatment responses in diverse settings.
  • Studies to improve outcomes for PWH accessing emergency care.
  • Modeling and testing alternative implementation approaches to improve uptake and scaling-up of effective interventions and reduce HIV disease transmission and progression in key populations.
  • Strategies to standardize use of unique patient identifiers for all patient records, tests, and health care engagement.
  • Development of data harmonization strategies to build a robust data analysis infrastructure for the application of large-scale data science approaches and technologies.
  • Implementation research to determine effective combination prevention strategies for both primary and secondary prevention.

Applications proposing the topics below will be considered non-responsive and will not be reviewed:

  • Projects proposing Phase III or Phase IV clinical trials .
  • Research using select agents .
  • Applications without the required collaborative partnership (at least one South African PD/PI from an eligible institution from South Africa and at least one collaborator from a U.S. institution/organization).

For more information, please refer to specific Questions and Answers located at this link: https://www.niaid.nih.gov/grants-contracts/questions-and-answers-US-South-Africa-collaborative-biomedical-research-phase-3-HIV-AIDS .

See Section VIII. Other Information for award authorities and regulations.

Investigators proposing NIH-defined clinical trials may refer to the Research Methods Resources website for information about developing statistical methods and study designs.

Section II. Award Information

Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

The  OER Glossary  and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO.

Optional: Accepting applications that either propose or do not propose clinical trial(s).

Need help determining whether you are doing a clinical trial?

Issuing IC and partner components intend to commit an estimated total of $3.8 million to fund 8-10 awards.

Application budgets are not expected to exceed $400,000 in direct costs per year and should reflect the actual needs of the proposed project.

The scope of the proposed project should determine the project period. The maximum project period is 5 years.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information

1. eligible applicants eligible organizations non-domestic (non-u.s.) entities (foreign organizations) eligible applicant organizations must be from south africa, as described below an eligible national research foundation (nrf) south african institution is a recognized south african public higher education or research institution such as a university, university of technology, science council, museum or other research institution as declared by the  department of science and innovation .  historically disadvantaged institutions (hdis) include: mangosuthu university of technology sefako makgatho health science university university of fort hare university of limpopo university of the western cape university of venda university of zululand walter sisulu university south african universities of technology include: cape peninsula university of technology central university of technology durban university of technology sol plaatje university tshwane university of technology university of mpumalanga vaal university of technology foreign organizations non-domestic (non-u.s.) entities (foreign organizations) are eligible to apply. non-domestic (non-u.s.) components of u.s. organizations are not eligible to apply. foreign components, as  defined in the nih grants policy statement , are allowed. required registrations applicant organizations applicant organizations must complete and maintain the following registrations as described in the how to apply- application guide to be eligible to apply for or receive an award. all registrations must be completed prior to the application being submitted. registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference the  nih grants policy statement section 2.3.9.2 electronically submitted applications  for additional information. system for award management (sam) – applicants must complete and maintain an active registration, which requires renewal at least annually . the renewal process may require as much time as the initial registration. sam registration includes the assignment of a commercial and government entity (cage) code for domestic organizations which have not already been assigned a cage code. nato commercial and government entity (ncage) code – foreign organizations must obtain an ncage code (in lieu of a cage code) in order to register in sam. unique entity identifier (uei) - a uei is issued as part of the sam.gov registration process. the same uei must be used for all registrations, as well as on the grant application. era commons - once the unique organization identifier is established, organizations can register with era commons in tandem with completing their grants.gov registrations; all registrations must be in place by time of submission. era commons requires organizations to identify at least one signing official (so) and at least one program director/principal investigator (pd/pi) account in order to submit an application. grants.gov – applicants must have an active sam registration in order to complete the grants.gov registration. program directors/principal investigators (pd(s)/pi(s)) all pd(s)/pi(s) must have an era commons account.  pd(s)/pi(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in era commons. if the pd/pi is also the organizational signing official, they must have two distinct era commons accounts, one for each role. obtaining an era commons account can take up to 2 weeks. eligible individuals (program director/principal investigator) any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the program director(s)/principal investigator(s) (pd(s)/pi(s)) is invited to work with their organization to develop an application for support. individuals from diverse backgrounds, including underrepresented racial and ethnic groups, individuals with disabilities, and women are always encouraged to apply for nih support. see, reminder: notice of nih's encouragement of applications supporting individuals from underrepresented ethnic and racial groups as well as individuals with disabilities , not-od-22-019 and notice of nih's interest in diversity, not-od-20-031 . for institutions/organizations proposing multiple pds/pis, visit the multiple program director/principal investigator policy and submission details in the senior/key person profile (expanded) component of the how to apply-application guide. required collaborative partnership a south african investigator(s) must serve as the pd/pi. additional south african investigator(s) may serve as part of a multi- pd/pi team or collaborators. at least one u.s. investigator(s) must serve as collaborator with the south african pd/pi (or the south african multi-pd/pi team). the south african pd/pis must be either permanently employed at an eligible south african research institution or be in a long-term contract (at least for the minimum of the duration of the project).  postgraduate students, full or part-time, are not eligible to serve as pds/pis. 2. cost sharing.

This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.2 Definition of Terms .

3. Additional Information on Eligibility

Number of Applications

Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

The NIH will not accept duplicate or highly overlapping applications under review at the same time, per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application . This means that the NIH will not accept:

  • A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
  • A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
  • An application that has substantial overlap with another application pending appeal of initial peer review (see  NIH Grants Policy Statement 2.3.9.4 Similar, Essentially Identical, or Identical Applications ).

Section IV. Application and Submission Information

1. requesting an application package.

The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission

It is critical that applicants follow the instructions in the Research (R) Instructions in the  How to Apply - Application Guide  except where instructed in this notice of funding opportunity to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.

Letter of Intent

Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review.

By the date listed in Part 1. Overview Information , prospective applicants are asked to submit a letter of intent that includes the following information:

  • Descriptive title of proposed activity
  • Name(s), address(es), and telephone number(s) of the PD(s)/PI(s)
  • Names of other key personnel
  • Participating institution(s)
  • Number and title of this funding opportunity

The letter of intent should be sent to:

Holly Curtis, PhD Office of Global Research National Institute of Allergy and Infectious Diseases (NIAID) Telephone: 301-761-5666 Email: [email protected]  

Page Limitations

All page limitations described in the How to Apply- Application Guide and the Table of Page Limits must be followed.

The following section supplements the instructions found in the How to Apply- Application Guide and should be used for preparing an application to this NOFO.

SF424(R&R) Cover

All instructions in the How to Apply - Application Guide must be followed.

SF424(R&R) Project/Performance Site Locations

All instructions in the How to Apply- Application Guide must be followed.

SF424(R&R) Other Project Information

All instructions in the How to Apply- Application Guide must be followed with the following additional instructions:

Facilities and Other Resources : In a clearly labeled section, applicants should include a description of project-specific resources, naming those resources that are provided by the PD/PIs and the collaborating partners, and a describe the plan for sharing and distribution of project-specific resources among the individuals performing specific elements of the research project (e.g., individual contributions of specific reagents, patient samples, compounds, and access to populations for epidemiologic studies).

Other Attachments : Two separate attachments should be submitted for this section: a Collaboration Plan and a Financial Management and Oversight Plan.

A Collaboration Plan (pdf file named Collaboration Plan) should be included that describes the interactions among the recipients (the South African PD/PIs and collaborators) in terms of plans for communications, processes for making decisions on scientific direction and planning activities, procedures for resolving conflicts, and fostering collaborations with the community, if applicable. Outline the combined roles and responsibilities of all participating partners in the research, including contingency plans addressing solutions to setbacks or delays.  Describe how the U.S. and South African investigators will draw on their unique expertise related to the research project.

A Financial Management and Oversight Plan (pdf file named Financial Plan) should be included that describes plans for implementing subcontracts and collaborations with research partners. Describe subcontract oversight activities to ensure adequate fiscal management and project timeliness. In this paragraph describe the minimum experience required by organizational representatives of HDIs or Universities of Technology to serve as subcontractors for financial engagement on the research project.  Describe the internal institutional plans and procedures to ensure that recipients will comply fully with all applicable U.S. Federal regulations, policies, and Guidelines for research involving vertebrate animals and human subjects, including for human subjects the evaluation of risks and protections in project proposals and appropriate ethical oversight of funded projects. 

SF424(R&R) Senior/Key Person Profile

R&r or modular budget.

In the budget justification section, applicants should demonstrate how the proposed budget will be distributed among the PD/PIs and collaborative partners.  Applicants are required to use the majority of funds to support work to be performed at the South African institution(s), with no less than fifty percent (50%) of the total budget costs directly supporting the South African component(s) of the research project. The 50% minimum applies to the entire project, not each budget year.

R&R Subaward Budget

All instructions in the How to Apply-Application Guide must be followed.

PHS 398 Cover Page Supplement

Phs 398 research plan.

All instructions in the How to Apply- Application Guide must be followed, with the following additional instructions:

Specific Aims:  Describe the specific aims of the project and indicate how the specific aims will be accomplished by the PD/PIs and collaborators.

Research Strategy:

  • Describe how the outcomes from the research project support the global health efforts to monitor, understand, treat, or prevent disease.
  • Provide the scope of research conducted by each member of the research team and discuss how the PD/PIs and collaborators, and key personnel will be involved in the execution of the research.
  • If applicable, provide a description of the research activities or experiences provided through the proposed research project(s) that will engage scientists from under-resourced institutions (HDIs and other South African Universities of Technology) that have a demonstrated commitment to biomedical research but have limited resources or experience, leading to the establishment or enhancement of research skills and expertise. Describe the specific role of the participating scientist in the proposed project and how their role contributes to the overall success of the proposed research.   
  • Provide a plan for monitoring the day-to-day activities of the research and remediating any identified delays or setbacks in the implementation of the research project.
  • Describe potential collaborations and involvement of community groups, local organizations, or other institutions in the research project.

Letters of Support:  Applicants from the U.S. and South Africa must include a Letter of Support signed by the respective institutional official agreeing to provide institutional support for the proposed research project.

Resource Sharing Plan : Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the How to Apply- Application Guide.

Other Plan(s): 

All instructions in the How to Apply-Application Guide must be followed, with the following additional instructions:

  • All applicants planning research (funded or conducted in whole or in part by NIH) that results in the generation of scientific data are required to comply with the instructions for the Data Management and Sharing Plan. All applications, regardless of the amount of direct costs requested for any one year, must address a Data Management and Sharing Plan.

Appendix:  Only limited Appendix materials are allowed. Follow all instructions for the Appendix as described in the How to Apply- Application Guide.

  • No publications or other material, with the exception of blank questionnaires or blank surveys, may be included in the Appendix.

PHS Human Subjects and Clinical Trials Information

When involving human subjects research, clinical research, and/or NIH-defined clinical trials (and when applicable, clinical trials research experience) follow all instructions for the PHS Human Subjects and Clinical Trials Information form in the How to Apply- Application Guide, with the following additional instructions:

If you answered “Yes” to the question “Are Human Subjects Involved?” on the R&R Other Project Information form, you must include at least one human subjects study record using the Study Record: PHS Human Subjects and Clinical Trials Information form or Delayed Onset Study record.

Study Record: PHS Human Subjects and Clinical Trials Information

Delayed Onset Study

Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start).All instructions in the How to Apply- Application Guide must be followed.

PHS Assignment Request Form

Foreign organizations.

Foreign (non-U.S.) organizations must follow policies described in the NIH Grants Policy Statement , and procedures for foreign organizations described throughout the How to Apply- Application Guide.

3. Unique Entity Identifier and System for Award Management (SAM)

See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov

4. Submission Dates and Times

Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday , the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons , NIH’s electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time.  If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications .

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in the How to Apply-Application Guide.

5. Intergovernmental Review (E.O. 12372)

This initiative is not subject to intergovernmental review.

6. Funding Restrictions

All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement .

Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost.

Applications must be submitted electronically following the instructions described in the How to Apply Application Guide. Paper applications will not be accepted.

Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.

For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply – Application Guide . If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII.

Important reminders:

All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form . Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH. See Section III of this NOFO for information on registration requirements.

The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization’s profile in the eRA Commons and for the System for Award Management. Additional information may be found in the How to Apply Application Guide.

See more tips for avoiding common errors.

Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review and responsiveness by components of participating organizations, NIH. Applications that are incomplete, non-compliant and/or nonresponsive will not be reviewed.

Recipients or subrecipients must submit any information related to violations of federal criminal law involving fraud, bribery, or gratuity violations potentially affecting the federal award. See Mandatory Disclosures,  2 CFR 200.113 and  NIH Grants Policy Statement Section 4.1.35 .

Send written disclosures to the NIH Chief Grants Management Officer listed on the Notice of Award for the IC that funded the award and to the  HHS Office of Inspector Grant Self Disclosure Program at  [email protected] .

Post Submission Materials

Applicants are required to follow the instructions for post-submission materials, as described in the policy

Section V. Application Review Information

1. criteria.

Only the review criteria described below will be considered in the review process. Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system.

Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following scored review criteria and additional review criteria (as applicable for the project proposed). An application does not need to be strong in all categories to be judged likely to have a major scientific impact.

Reviewers will evaluate Factors 1, 2 and 3 in the determination of scientific merit, and in providing an overall impact score. In addition, Factors 1 and 2 will each receive a separate criterion score. 

Significance

  • Evaluate the importance of the proposed research in the context of current scientific challenges and opportunities, either for advancing knowledge within the field, or more broadly. Assess whether the application addresses an important gap in knowledge in the field, would solve a critical problem, or create a valuable conceptual or technical advance.
  • Evaluate the rationale for undertaking the study, the rigor of the scientific background for the work (e.g., prior literature and/or preliminary data) and whether the scientific background justifies the proposed study.
  • Evaluate the extent to which innovation influences the importance of undertaking the proposed research. Note that while technical or conceptual innovation can influence the importance of the proposed research, a project that is not applying novel concepts or approaches may be of critical importance for the field.
  • Evaluate whether the proposed work applies novel concepts, methods or technologies or uses existing concepts, methods, technologies in novel ways, to enhance the overall impact of the project.
  • Evaluate the scientific quality of the proposed work. Evaluate the likelihood that compelling, reproducible findings will result (rigor) and assess whether the proposed studies can be done well and within the timeframes proposed (feasibility).
  • Evaluate the potential to produce unbiased, reproducible, robust data.
  • Evaluate the rigor of experimental design and whether appropriate controls are in place.
  • Evaluate whether the sample size is sufficient and well-justified.
  • Assess the quality of the plans for analysis, interpretation, and reporting of results.
  • Evaluate whether the investigators presented adequate plans to address relevant biological variables, such as sex or age, in the design, analysis, and reporting.
  • the rigor of the intervention or study manipulation (if applicable to the study design).
  • whether outcome variables are justified.
  • whether the results will be generalizable or, in the case of a rare disease/special group, relevant to the particular subgroup.
  • whether the sample is appropriate and sufficiently diverse to address the proposed question(s).
  • For applications involving human subjects, including clinical trials, assess the adequacy of inclusion plans as appropriate for the scientific goals of the research. Considerations of appropriateness may include disease/condition/behavior incidence, prevalence, or population burden, population representation, and/or current state of the science.

Feasibility:

  • Evaluate whether the proposed approach is sound and achievable, including plans to address problems or new challenges that emerge in the work. For proposed studies in which feasibility may be less certain, evaluate whether the uncertainty is balanced by the potential for major advances.
  • For applications involving human subjects, including clinical trials, evaluate the adequacy and feasibility of the plan to recruit and retain an appropriately diverse population of participants. Additionally, evaluate the likelihood of successfully achieving the proposed enrollment based on age, racial, ethnic, and sex/gender categories.
  • For clinical trial applications, evaluate whether the study timeline and milestones are feasible.

Specific to this NOFO:

  • Evaluate to what extent the collaboration plan suits the proposed project.
  • Evaluate how adequate the plans are for monitoring progress of the research. 
  • Evaluate how well the applicant has provided remedies or solutions to potential setbacks or delays.

Investigator(s)

Evaluate whether the investigator(s) have demonstrated background, training, and expertise, as appropriate for their career stage, to conduct the proposed work. For Multiple Principal Investigator (MPI) applications, assess the quality of the leadership plan to facilitate coordination and collaboration.

Environment

Evaluate whether the institutional resources are appropriate to ensure the successful execution of the proposed work.

  • Evaluate how well the plans for integrating the proposed work of the U.S. and South African investigators draw on their unique expertise related to the research project.
  • If proposed, evaluate the extent to which the experience of the combined collaborative partnership between the U.S. and South African PD/PIs with respect to providing unique research experiences for scientists from under-resourced institutions (HDIs and other South African Universities of Technology) to advance their own research expertise.
  • Evaluate to what degree the applicant has described the plan for sharing and distribution of project-specific resources among all investigators working on the research project.
  • Evaluate h ow well the objectives for financial management and oversight are defined, and how well the plan describes the process for engaging other institutions in the research funding process.

As applicable for the project proposed, reviewers will consider the following additional items while determining scientific and technical merit, but will not give criterion scores for these items, and should consider them in providing an overall impact score.

For research that involves human subjects but does not involve one of the categories of research that are exempt under 45 CFR Part 46, evaluate the justification for involvement of human subjects and the proposed protections from research risk relating to their participation according to the following five review criteria: 1) risk to subjects; 2) adequacy of protection against risks; 3) potential benefits to the subjects and others; 4) importance of the knowledge to be gained; and 5) data and safety monitoring for clinical trials.

For research that involves human subjects and meets the criteria for one or more of the categories of research that are exempt under 45 CFR Part 46, evaluate: 1) the justification for the exemption; 2) human subjects involvement and characteristics; and 3) sources of materials. For additional information on review of the Human Subjects section, please refer to the  Guidelines for the Review of Human Subjects .

When the proposed research includes Vertebrate Animals, evaluate the involvement of live vertebrate animals according to the following criteria: (1) description of proposed procedures involving animals, including species, strains, ages, sex, and total number to be used; (2) justifications for the use of animals versus alternative models and for the appropriateness of the species proposed; (3) interventions to minimize discomfort, distress, pain and injury; and (4) justification for euthanasia method if NOT consistent with the AVMA Guidelines for the Euthanasia of Animals. For additional information on review of the Vertebrate Animals section, please refer to the  Worksheet for Review of the Vertebrate Animals Section .

When the proposed research includes Biohazards, evaluate whether specific materials or procedures that will be used are significantly hazardous to research personnel and/or the environment, and whether adequate protection is proposed.

As applicable, evaluate the full application as now presented.

As applicable, evaluate the progress made in the last funding period.

As applicable, evaluate the appropriateness of the proposed expansion of the scope of the project.

As applicable for the project proposed, reviewers will consider each of the following items, but will not give scores for these items, and should not consider them in providing an overall impact score.

For projects involving key biological and/or chemical resources, evaluate the brief plans proposed for identifying and ensuring the validity of those resources.

Evaluate whether the budget and the requested period of support are fully justified and reasonable in relation to the proposed research.

2. Review and Selection Process Applications will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s) convened by the Center for Scientific Review (CSR), in accordance with NIH peer review policies and practices , using the stated review criteria. Assignment to a Scientific Review Group will be shown in the eRA Commons. As part of the scientific peer review, all applications will receive a written critique. Applications may undergo a selection process in which only those applications deemed to have the highest scientific and technical merit (generally the top half of applications under review) will be discussed and assigned an overall impact score. Appeals of initial peer review will not be accepted for applications submitted in response to this NOFO. Applications will be assigned on the basis of established PHS referral guidelines to the appropriate NIH Institute or Center. Applications will compete for available funds with all other recommended applications submitted in response to this NOFO. Following initial peer review, recommended applications will receive a second level of review by the appropriate national Advisory Council or Board. The following will be considered in making funding decisions: Scientific and technical merit of the proposed project as determined by scientific peer review. Availability of funds. Relevance of the proposed project to program priorities. Geographic distribution of South African Institutions. If the application is under consideration for funding, NIH will request "just-in-time" information from the applicant as described in the  NIH Grants Policy Statement Section 2.5.1. Just-in-Time Procedures . This request is not a Notice of Award nor should it be construed to be an indicator of possible funding. Prior to making an award, NIH reviews an applicant’s federal award history in SAM.gov to ensure sound business practices. An applicant can review and comment on any information in the Responsibility/Qualification records available in SAM.gov. NIH will consider any comments by the applicant in the Responsibility/Qualification records in SAM.gov to ascertain the applicant’s integrity, business ethics, and performance record of managing Federal awards per 2 CFR Part 200.206 “Federal awarding agency review of risk posed by applicants.” This provision will apply to all NIH grants and cooperative agreements except fellowships. 3. Anticipated Announcement and Award Dates

After the peer review of the application is completed, the PD/PI will be able to access his or her Summary Statement (written critique) via the  eRA Commons . Refer to Part 1 for dates for peer review, advisory council review, and earliest start date.

Information regarding the disposition of applications is available in the  NIH Grants Policy Statement Section 2.4.4 Disposition of Applications .

Section VI. Award Administration Information

1. award notices.

A Notice of Award (NoA) is the official authorizing document notifying the applicant that an award has been made and that funds may be requested from the designated HHS payment system or office. The NoA is signed by the Grants Management Officer and emailed to the recipient’s business official.

In accepting the award, the recipient agrees that any activities under the award are subject to all provisions currently in effect or implemented during the period of the award, other Department regulations and policies in effect at the time of the award, and applicable statutory provisions.

Recipients must comply with any funding restrictions described in  Section IV.6. Funding Restrictions . Any pre-award costs incurred before receipt of the NoA are at the applicant's own risk.  For more information on the Notice of Award, please refer to the  NIH Grants Policy Statement Section 5. The Notice of Award and NIH Grants & Funding website, see  Award Process.

Individual awards are based on the application submitted to, and as approved by, the NIH and are subject to the IC-specific terms and conditions identified in the NoA.

ClinicalTrials.gov: If an award provides for one or more clinical trials. By law (Title VIII, Section 801 of Public Law 110-85), the "responsible party" must register and submit results information for certain “applicable clinical trials” on the ClinicalTrials.gov Protocol Registration and Results System Information Website ( https://register.clinicaltrials.gov ). NIH expects registration and results reporting of all trials whether required under the law or not. For more information, see https://grants.nih.gov/policy/clinical-trials/reporting/index.htm

Institutional Review Board or Independent Ethics Committee Approval: Recipient institutions must ensure that all protocols are reviewed by their IRB or IEC. To help ensure the safety of participants enrolled in NIH-funded studies, the recipient must provide NIH copies of documents related to all major changes in the status of ongoing protocols.

Data and Safety Monitoring Requirements: The NIH policy for data and safety monitoring requires oversight and monitoring of all NIH-conducted or -supported human biomedical and behavioral intervention studies (clinical trials) to ensure the safety of participants and the validity and integrity of the data. Further information concerning these requirements is found at http://grants.nih.gov/grants/policy/hs/data_safety.htm and in the application instructions (SF424 (R&R) and PHS 398).

Investigational New Drug or Investigational Device Exemption Requirements: Consistent with federal regulations, clinical research projects involving the use of investigational therapeutics, vaccines, or other medical interventions (including licensed products and devices for a purpose other than that for which they were licensed) in humans under a research protocol must be performed under a Food and Drug Administration (FDA) investigational new drug (IND) or investigational device exemption (IDE).

2. Administrative and National Policy Requirements

The following Federal wide and HHS-specific policy requirements apply to awards funded through NIH:

  • The rules listed at 2 CFR Part 200 , Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards.
  • All NIH grant and cooperative agreement awards include the NIH Grants Policy Statement as part of the terms and conditions in the Notice of Award (NoA). The NoA includes the requirements of this NOFO. For these terms of award, see the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: General and Part II: Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions for Specific Types of Grants, Recipients, and Activities .
  • HHS recognizes that NIH research projects are often limited in scope for many reasons that are nondiscriminatory, such as the principal investigator’s scientific interest, funding limitations, recruitment requirements, and other considerations. Thus, criteria in research protocols that target or exclude certain populations are warranted where nondiscriminatory justifications establish that such criteria are appropriate with respect to the health or safety of the subjects, the scientific study design, or the purpose of the research. For additional guidance regarding how the provisions apply to NIH grant programs, please contact the Scientific/Research Contact that is identified in Section VII under Agency Contacts of this NOFO.

All federal statutes and regulations relevant to federal financial assistance, including those highlighted in  NIH Grants Policy Statement Section 4 Public Policy Requirements, Objectives and Other Appropriation Mandates.

Recipients are responsible for ensuring that their activities comply with all applicable federal regulations.  NIH may terminate awards under certain circumstances.  See  2 CFR Part 200.340 Termination and  NIH Grants Policy Statement Section 8.5.2 Remedies for Noncompliance or Enforcement Actions: Suspension, Termination, and Withholding of Support . 

Consistent with the 2023 NIH Policy for Data Management and Sharing, when data management and sharing is applicable to the award, recipients will be required to adhere to the Data Management and Sharing requirements as outlined in the NIH Grants Policy Statement . Upon the approval of a Data Management and Sharing Plan, it is required for recipients to implement the plan as described.

4. Reporting

When multiple years are involved, recipients will be required to submit the  Research Performance Progress Report (RPPR)  annually and financial statements as required in the NIH Grants Policy Statement Section 8.4.1 Reporting.  To learn more about post-award monitoring and reporting, see the NIH Grants & Funding website, see Post-Award Monitoring and Reporting .

A final RPPR, invention statement, and the expenditure data portion of the Federal Financial Report are required for closeout of an award, as described in the NIH Grants Policy Statement Section 8.6 Closeout . NIH NOFOs outline intended research goals and objectives. Post award, NIH will review and measure performance based on the details and outcomes that are shared within the RPPR, as described at 2 CFR Part 200.301.

Section VII. Agency Contacts

We encourage inquiries concerning this funding opportunity and welcome the opportunity to answer questions from potential applicants.

eRA Service Desk (Questions regarding ASSIST, eRA Commons, application errors and warnings, documenting system problems that threaten submission by the due date, and post-submission issues)

Finding Help Online:  https://www.era.nih.gov/need-help  (preferred method of contact) Telephone: 301-402-7469 or 866-504-9552 (Toll Free)

General Grants Information (Questions regarding application instructions, application processes, and NIH grant resources) Email:  [email protected]  (preferred method of contact) Telephone: 301-480-7075

Grants.gov Customer Support (Questions regarding Grants.gov registration and Workspace) Contact Center Telephone: 800-518-4726 Email:  [email protected]

Brian Remortel, M.P.H. National Institute of Allergy and Infectious Diseases (NIAID) Telephone: 240-292-4816 Email: [email protected]  

Geraldina Dominguez, Ph.D. National Cancer Institute (NCI) Telephone: 301-920-6044  Email: [email protected]  

Sonia Lee, Ph.D. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Telephone: 301-594-4783 Email: [email protected]  

Christopher Gordon, Ph.D. National Institute of Mental Health (NIMH) Telephone: 301-443-1613 Email: [email protected]  

Kendall Bryant, Ph.D. National Institute on Alcohol Abuse and Alcoholism (NIAAA) Telephone: 301-402-0332 Email: [email protected]  

David Chang, Ph.D. Office of AIDS Research (OAR) Telephone: 301-827-4221 Email:  [email protected]  

Dr Michelle Mulder Ph.D. South African Medical Research Council Telephone: +27 21 938 0937 Email: [email protected]  

Raul Rojas, Ph.D. Center for Scientific Review (CSR) Telephone: 301-435-0492 Email:  [email protected]  

Annie Grimes National Institute of Allergy and Infectious Diseases (NIAID) Telephone: 301-761-7315 Email: [email protected]  

Dawn Mitchum National Cancer Institute (NCI) Telephone: 240-276-5699 Email: [email protected]   Margaret Young Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Telephone: 301-642-4552 Email: [email protected]  

Rita Sisco National Institute of Mental Health (NIMH) Telephone: 301-443-2805 Email: [email protected]   

Judy Fox National Institute on Alcohol Abuse and Alcoholism (NIAAA) Telephone: 301-443-4704 Email: [email protected]    

Section VIII. Other Information

Recently issued trans-NIH policy notices may affect your application submission. A full list of policy notices published by NIH is provided in the NIH Guide for Grants and Contracts . All awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement .

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

NIH Office of Extramural Research Logo

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    A cover letter should be addressed to a named person i.e. "Dear Professor Smith". For a PhD application, this will usually be the PhD supervisor, but may be a specific person in charge of recruitment. If you are still unsure who to address the cover letter to, it should be directed to the Head of Department.

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    No part of this publication may be reproduced in any way without the express written permission of the Harvard University Faculty of Arts & Sciences Office of Career Services. 8/19 Ofice of Career Services Harvard University Faculty of Arts & Sciences Cambridge, MA 02138 Phone: (617) 495-2595 www.ocs.fas.harvard.edu. Resumes and Cover Letters.

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    Biomedical Scientist Cover Letter Example 1. I am excited to be applying for the Biomedical Scientist position at ABC Labs. I have a Ph.D. in Molecular Biology and more than five years of experience in the field of biomedical research. I am confident that I have the skills and experience to excel in this role and contribute to ABC Labs ...

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    cover letters, whether you are applying for an academic position or a non-academic position - or both. It is designed primarily for Cambridge PhD students and postdoctoral staff. Undergraduates and Masters students should ask for the edition of CVs and Cover Letters written especially for them, available free from the Careers Service. Each ...

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    Tailor the elements of your application to the program for which you are applying even if this means writing multiple cover letters or resumes. The medical school recommendations that are on-file at your school will probably not address the issues that are important to a biomedical research training program, e.g., your technical skills, your ...

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